Related Product Information for Taf9b recombinant protein
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.
Uniprot Description
Essential for cell viability. TAF9 and TAF9L are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription ().
Product Notes
The Taf9b taf9b (Catalog #
AAA1443081) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-258, full length protein. The amino acid sequence is listed below: MEPSKMAPLK NAPRDALVMA QILKDMGITD YEPRVINQML EFAFRYVTTI LDDAKIYSSH AKKPTVDADD VRLAIQCRAD QSFTSPPPRD FLLDIARQKN QTPLPLIKPY AGPRLPPDRY CLTAPNYRLK SLVKKGPNQG RLVPRLSVGA VSSRPTTPTV APPQAVSVPN KVATPVSVTS QRFAVQIPTS QSTPAKPAPA ATSVQNVLIN PSMIGSKNIL ITTNMVSSQS TATDSNPLKR KHDDDDDDDD DDDDNDTM.
It is sometimes possible for the material contained within the vial of
"Transcription initiation factor TFIID subunit 9B (Taf9b), Recombinant Protein" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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industry standard. AAA Biotech
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purchaser may be intending to use a product outside of our accepted criteria.
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