TATA box-binding protein-associated factor RNA polymerase I subunit A (Taf1a) Recombinant Protein | Taf1a recombinant protein
Recombinant Mouse TATA box-binding protein-associated factor RNA polymerase I subunit A (Taf1a)
Gene Names
Taf1a; TAFI48; mTAFI48
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
TATA box-binding protein-associated factor RNA polymerase I subunit A (Taf1a); Recombinant Mouse TATA box-binding protein-associated factor RNA polymerase I subunit A (Taf1a); Taf1a recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-453, Full length protein
Sequence
MMSDFGEELTKLAVAEDNPETSVLSKTGMHFPWLHKHVEAVVTGGKKRKDFAQTTSACLSFIQEALLKHQWQQAAEYMHSYLQTLEDSDTDKRQAAPEIIWKLGSEILFYHPKSNVETFNSFADRMKNIGVLNYLKISLQHALYLLHHGMLDDANRNLSKAETWRYGEKSSSQEVLINLVQAYKGLLQYYTWTRKKMELSKLDEDDYAYAAKTRTMLSQSCKTSTNICALVKTPGVWDPFVKSYVEMLEFYGDQDGAREMLTNYAYDEKFPSNPNAHVYLYEFLKREKAPRAKLISVLKILHEIVPSHTLMLEFHTLLRKSDTEEHQKLGLSVLFEVLDFAGCNKNITAWKYLAKYLKQILVGSHHEWVEEEWKSRRNWWPAFHFSFFWAKSDWKADTDLACEKAFVAGVLLGKGCKYFRYILKQDHETLKKKIKRMKKSVKKYTIVNPGVHT
Sequence Length
453
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Taf1a recombinant protein
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,718 Da
NCBI Official Full Name
TATA box-binding protein-associated factor RNA polymerase I subunit A isoform 2
NCBI Official Synonym Full Names
TATA-box binding protein associated factor, RNA polymerase I, A
NCBI Official Symbol
Taf1a
NCBI Official Synonym Symbols
TAFI48; mTAFI48
NCBI Protein Information
TATA box-binding protein-associated factor RNA polymerase I subunit A
UniProt Protein Name
TATA box-binding protein-associated factor RNA polymerase I subunit A
Protein Family
UniProt Gene Name
Taf1a
UniProt Synonym Gene Names
TAFI48; TBP-associated factor 1A
Uniprot Description
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits ().
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Product Notes
The Taf1a taf1a (Catalog #AAA954692) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-453, Full length protein. The amino acid sequence is listed below: MMSDFGEELT KLAVAEDNPE TSVLSKTGMH FPWLHKHVEA VVTGGKKRKD FAQTTSACLS FIQEALLKHQ WQQAAEYMHS YLQTLEDSDT DKRQAAPEII WKLGSEILFY HPKSNVETFN SFADRMKNIG VLNYLKISLQ HALYLLHHGM LDDANRNLSK AETWRYGEKS SSQEVLINLV QAYKGLLQYY TWTRKKMELS KLDEDDYAYA AKTRTMLSQS CKTSTNICAL VKTPGVWDPF VKSYVEMLEF YGDQDGAREM LTNYAYDEKF PSNPNAHVYL YEFLKREKAP RAKLISVLKI LHEIVPSHTL MLEFHTLLRK SDTEEHQKLG LSVLFEVLDF AGCNKNITAW KYLAKYLKQI LVGSHHEWVE EEWKSRRNWW PAFHFSFFWA KSDWKADTDL ACEKAFVAGV LLGKGCKYFR YILKQDHETL KKKIKRMKKS VKKYTIVNPG VHT. It is sometimes possible for the material contained within the vial of "TATA box-binding protein-associated factor RNA polymerase I subunit A (Taf1a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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