Mouse synaptotagmin XIV ELISA Kit | SYT14 elisa kit
Mouse Synaptotagmin-14, SYT14 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the synaptotagmin family. The encoded protein may be involved in membrane trafficking. Disruption of a similar gene in human has been associated with autosomal recessive spinocerebellar ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Uniprot Description
SYT14: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent. Defects in SYT14 are the cause of spinocerebellar ataxia autosomal recessive type 11 (SCAR11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR11 is associated with psychomotor retardation. Belongs to the synaptotagmin family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: clathrin binding; protein homodimerization activity; syntaxin binding; calcium-dependent phospholipid binding; protein heterodimerization activity; phospholipid binding; calcium ion binding
Biological Process: vesicle fusion; synaptic vesicle exocytosis
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Product Notes
The Mouse SYT14 syt14 (Catalog #AAA9332284) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332284 ELISA Kit recognizes Mouse SYT14. It is sometimes possible for the material contained within the vial of "synaptotagmin XIV, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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