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Chemical Structure (Chemical structure of Nonactin (SIH-372), a Ammonium ionophore. CAS #: 6833-84-7. Molecular Formula: C40H64O12. Molecular Weight: 736.93 g/mol.)

Nonactin Small Molecule

Nonactin

Purity
>98% (TLC)
Synonyms
Nonactin; Ammonium ionophore; (1R; 2R; 5R; 7R; 10S; 11S; 14S; 16S; 19R; 20¬R; 23R; 25R; 28S; 29S; 32S; 34S)-2; 5; 11; 14; 20; 23; 29; 32-O¬ctamethyl-4; 13; 22; 31; 37; 38; 39; 40-octaoxapentacyclo-[32.2.1.17; 10.116; 19.125; 28]tetracontane-3; 12; 21; 3¬0-tetrone; Nonactin small molecule
Ordering
For Research Use Only!
Host
Synthetic
Purity/Purification
>98% (TLC)
Form/Format
White to off-white solid
Solubility
Soluble in DMSO, methanol, ethanol (10 mM), dichloromethane and ethyl acetate. Insoluble in water.
CAS Number
6833-84-7
Molecular Formula
C40H64O12
SMILES
C[C@@H]1C[C@H]2CC[C@H](O2)[C@@H](C(=O)O[C@H](C[C@@H]3CC[C@@H](O3)[C@H](C(=O)O[C@@H](C[C@H]4CC[C@H](O4)[C@@H](C(=O)O[C@H](C[C@@H]5CC[C@@H](O5)[C@H](C(=O)O1)C)C)C)C)C)C)C
InChI
1S/C40H64O12/c1-21-17-29-9-13-34(49-29)26(6)38(42)46-23(3)19-31-11-15-36(51-31)28(8)40(44)48-24(4)20-32-12-16-35(52-32)27(7)39(43)47-22(2)18-30-10-14-33(50-30)25(5)37(41)45-21/h21-36H,9-20H2,1-8H3/t21-,22+,23+,24-,25-,26+,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-
InChI Key
RMIXHJPMNBXMBU-QIIXEHPYSA-N
PubChem CID
72519
Preparation and Storage
Store at -20 degree C.

Chemical Structure

(Chemical structure of Nonactin (SIH-372), a Ammonium ionophore. CAS #: 6833-84-7. Molecular Formula: C40H64O12. Molecular Weight: 736.93 g/mol.)

Chemical Structure (Chemical structure of Nonactin (SIH-372), a Ammonium ionophore. CAS #: 6833-84-7. Molecular Formula: C40H64O12. Molecular Weight: 736.93 g/mol.)
Related Product Information for Nonactin small molecule
Nonactin also known as Polynanctin, Werramycin A is a member of the family of cyclic ionophores. It has a high selectivity for ammonium ions and for this reason is also known as "ammonium ionophore". It was first isolated by Corbaz et al. in 1955 from bacterial strains (1). To understand the required stereochemistry for an efficient bacterial and ion binding, various isothermal calorimetric measurements were performed with K+, Na+ and NH4+. Nonactin is active against a range of gram positive organisms and has a high selectivity for K+ (2).
Product Categories/Family for Nonactin small molecule
References
1. Corbaz R., et al. (1955) Helvetica Chimica Acta 38(60): 1445-48. 2. Kushe B., Smith A., McGuirl M., Priestley N., (2009) J Am Chem Soc 131(47): 17555-165.

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Product Notes

The Nonactin (Catalog #AAA808076) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Nonactin, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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