Western Blot (WB)
(WB Suggested Anti-NT5M Antibody Titration: 0.2-1 ug/mlPositive Control: A549 cell lysateNT5M is supported by BioGPS gene expression data to be expressed in A549)
Rabbit NT5M Polyclonal Antibody | anti-NT5M antibody
NT5M antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-NT5M Antibody Titration: 0.2-1 ug/mlPositive Control: A549 cell lysateNT5M is supported by BioGPS gene expression data to be expressed in A549)
Western Blot (WB)
(WB Suggested Anti-NT5M Antibody Titration: 0.2-1 ug/mlPositive Control: A549 cell lysateNT5M is supported by BioGPS gene expression data to be expressed in A549)
Target Description: This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Uniprot Description
NT5M: Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Nucleotide Metabolism - pyrimidine; Mitochondrial; EC 3.1.3.-; Nucleotide Metabolism - purine; Phosphatase (non-protein); DNA replication
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: mitochondrion; mitochondrial matrix
Molecular Function: 5'-nucleotidase activity; metal ion binding; nucleotide binding; nucleotidase activity
Biological Process: pyrimidine nucleoside catabolic process; pyrimidine base metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; pyrimidine deoxyribonucleotide catabolic process; dUMP catabolic process; DNA replication
Research Articles on NT5M
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Product Notes
The NT5M nt5m (Catalog #AAA3213326) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NT5M antibody - N-terminal region reacts with Cow, Dog, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NT5M can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NT5M nt5m for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ALRVLVDMDG VLADFEGGFL RKFRARFPDQ PFIALEDRRG FWVSEQYGRL. It is sometimes possible for the material contained within the vial of "NT5M, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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