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GAT1 Blocking Peptide | SLC6A1 blocking peptide

GAT1 Blocking Peptide

Gene Names
SLC6A1; MAE; GAT1; GABATR; GABATHG
Reactivity
Human, Mouse, Rat
Applications
Blocking (BL)
Purity
>85%
Synonyms
GAT1; GAT1 Blocking Peptide; GABATR; GABT1; Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1; SLC6A1 blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
599
Applicable Applications for SLC6A1 blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for SLC6A1 blocking peptide
The peptide is used to block Anti-GAT1 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,074 Da
NCBI Official Full Name
sodium- and chloride-dependent GABA transporter 1
NCBI Official Synonym Full Names
solute carrier family 6 member 1
NCBI Official Symbol
SLC6A1
NCBI Official Synonym Symbols
MAE; GAT1; GABATR; GABATHG
NCBI Protein Information
sodium- and chloride-dependent GABA transporter 1
UniProt Protein Name
Sodium- and chloride-dependent GABA transporter 1
UniProt Gene Name
SLC6A1
UniProt Synonym Gene Names
GABATR; GABT1; GAT1; GAT-1
UniProt Entry Name
SC6A1_HUMAN

NCBI Description

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009]

Uniprot Description

SLC6A1: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: integral to membrane; integral to plasma membrane; membrane; neuron projection; plasma membrane

Molecular Function: gamma-aminobutyric acid:sodium symporter activity

Biological Process: gamma-aminobutyric acid transport; neurotransmitter transport; synaptic transmission

Disease: Myoclonic-atonic Epilepsy

Research Articles on SLC6A1

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Product Notes

The SLC6A1 slc6a1 (Catalog #AAA8247928) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The GAT1 Blocking Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GAT1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the SLC6A1 slc6a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAT1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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