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Neurocan Blocking Peptide | NCAN blocking peptide

Neurocan Blocking Peptide

Gene Names
NCAN; CSPG3
Reactivity
Human, Mouse, Rat
Applications
Blocking (BL)
Purity
>85%
Synonyms
Neurocan; Neurocan Blocking Peptide; CSPG3; NEUR; Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
1321
Applicable Applications for NCAN blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for NCAN blocking peptide
The peptide is used to block Anti-Neurocan Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
143,093 Da
NCBI Official Full Name
neurocan core protein
NCBI Official Synonym Full Names
neurocan
NCBI Official Symbol
NCAN
NCBI Official Synonym Symbols
CSPG3
NCBI Protein Information
neurocan core protein; neurocan proteoglycan; chondroitin sulfate proteoglycan 3 (neurocan)
UniProt Protein Name
Neurocan core protein
Protein Family
UniProt Gene Name
NCAN
UniProt Synonym Gene Names
CSPG3; NEUR
UniProt Entry Name
NCAN_HUMAN

NCBI Description

Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002]

Uniprot Description

CSPG3: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid. Belongs to the aggrecan/versican proteoglycan family.

Protein type: Secreted; Secreted, signal peptide; Cell adhesion

Chromosomal Location of Human Ortholog: 19p12

Cellular Component: proteinaceous extracellular matrix; lysosomal lumen; Golgi lumen; extracellular region

Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding

Biological Process: chondroitin sulfate metabolic process; axon guidance; extracellular matrix organization and biogenesis; chondroitin sulfate biosynthetic process; central nervous system development; glycosaminoglycan metabolic process; carbohydrate metabolic process; chondroitin sulfate catabolic process; regulation of synapse structural plasticity; pathogenesis; cell adhesion; skeletal development; dermatan sulfate biosynthetic process

Research Articles on NCAN

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Product Notes

The NCAN ncan (Catalog #AAA823294) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The Neurocan Blocking Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Neurocan can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the NCAN ncan for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurocan, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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