Structure
(Chemical structure of Camostat mesylate, a Serine protease inhibitor. CAS #: 59721-29-8. Molecular Formula: C20H22N4O5·CH3SO3H. Molecular Weight: 494.5 g/mol.)
Camostat mesylate, Inhibitor
Camostat mesylate
Purity
>98% (HPLC); NMR (conforms)
Synonyms
Camostat mesylate; 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate; FOY 305; FOY-S 980; Foipan mesylate; inhibitor
Host
Synthetic
Purity/Purification
>98% (HPLC); NMR (conforms)
Form/Format
Off-white powder
CAS No
59721-29-8
Molecular Forumla
C20H22N4O5 CH3SO3H
Solubility
May be dissolved in DMSO (50 mg/mL) or Water (50mg/mL)
SMILES
O=C(C2=CC=C(NC(N)=N)C=C2)OC1=CC=C(CC(OCC(N(C)C)=O)=O)C=C1.CS(=O)(O)=O
InChI
InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
InChIKey
FSEKIHNIDBATFG-UHFFFAOYSA-N
Safety Phrases
General Classification: Warning Hazard statements: H315-H319-H335-H400 Precautionary statements: P261-P273-P305 + P351 + P338
Preparation and Storage
-20 degree C
Structure
(Chemical structure of Camostat mesylate, a Serine protease inhibitor. CAS #: 59721-29-8. Molecular Formula: C20H22N4O5·CH3SO3H. Molecular Weight: 494.5 g/mol.)
Structure
(Chemical structure of Camostat mesylate, a Serine protease inhibitor. CAS #: 59721-29-8. Molecular Formula: C20H22N4O5·CH3SO3H. Molecular Weight: 494.5 g/mol.)
Related Product Information for Camostat mesylate, inhibitor
Serine protease inhibitor. Camostat mesylate is an orally active protease inhibitor. It inhibits the serine protease TMPRSS2 and partially blocks entry of SARS-Cov-2 (Covid-19) into lung cells and Human coronavirus NL63 into HeLa cells. It has also been used in some cancer treatments, against viral infections, and for inhibiting fibrosis in liver, kidney disease and pancreatitis.
Product Categories/Family for Camostat mesylate, inhibitor
References
1. Okuno M., et al. (2002). Front Biosci. 7 (4): d204-218.
2. Hsieh H. P., Hsu, J. T. (2007). Current Pharmaceutical Design. 13 (34): 3531–3542.
3. Kitamura K., Tomita K. (2012). Clinical and Experimental Nephrology. 16 (1): 44–48. 4. Kawase M., Shirato K., van der Hoek L., Taguchi F., Matsuyama S. (2012) J Virol. 86(12): 6537-6545. 5.. Hoffman M., et al. (2020) Cell: https://doi.org/10.1016/j.cell.2020.02.052
2. Hsieh H. P., Hsu, J. T. (2007). Current Pharmaceutical Design. 13 (34): 3531–3542.
3. Kitamura K., Tomita K. (2012). Clinical and Experimental Nephrology. 16 (1): 44–48. 4. Kawase M., Shirato K., van der Hoek L., Taguchi F., Matsuyama S. (2012) J Virol. 86(12): 6537-6545. 5.. Hoffman M., et al. (2020) Cell: https://doi.org/10.1016/j.cell.2020.02.052
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Product Notes
The Camostat mesylate (Catalog #AAA8005713) is an Inhibitor produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Camostat mesylate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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