Structure
Gabexate mesylate Biochemical
Gabexate mesylate
Purity
>=97%
Synonyms
Gabexate mesylate; FOY; Megacart; ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid; 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid ethyl ester mesylate; [Ethyl p-(6-guanidinohexanoyloxy) benzoate]methanesulfonate; Gabexate mesylate biochemical
Specificity
An inhibitor of serine proteases
Purity/Purification
>=97%
Form/Format
White solid
Solubilities
~25mg/ml in DMSO and DMF
Molecular Formula
C??H??N?O?S
InChi
InChI=1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2; 3)4/h7-10H; 2-6; 11H2; 1H3; (H4; 17; 18; 19);1H3; (H; 2; 3; 4)
InChi Key
DNTNDFLIKUKKOC-UHFFFAOYSA-N
SMILES
CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
CAS Number
56974-61-9
MDL Number
MFCD00210299
PubChem CID
6604561
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Structure
Structure
Related Product Information for Gabexate mesylate biochemical
Gabexate is an inhibitor of serine proteases. It inhibits plasma kallikrein, thrombin, plasmin, factor Xa with Ki values of 0.2uM, 0.97uM, 1.6uM and 8.5uM. It exerts an anticoagulant effect on the clotting activity of thrombin. It inhibits LPS-induced TNF-alpha production in monocytes by inhibiting activation of both NF-kappaB and activator protein-1. It slightly inhibits SARS-CoV-2 S-driven host cell entry in lung cells.
Product Categories/Family for Gabexate mesylate biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/6604561
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Product Notes
The Gabexate mesylate (Catalog #AAA8400498) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Gabexate mesylate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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