NCAPG2 sirna

NCAPG2 siRNA (Human)

Cat. Num. AAA8218972

• Gene Names: NCAPG2; MTB; CAPG2; LUZP5; CAP-G2; hCAP-G2
• Reactivity: Human
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: NCAPG2; NCAPG2 siRNA (Human); LUZP5; Condensin-2 complex subunit G2; Chromosome-associated protein G2; CAP-G2; hCAP-G2; Leucine zipper protein 5; Non-SMC condensin II complex subunit G2; NCAPG2 sirna

• Host: Synthetic
• Reactivity: Human
• Specificity: NCAPG2 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 1143

• Applicable Applications for NCAPG2 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human NCAPG2 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for NCAPG2 sirna

siRNA to inhibit NCAPG2 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 530339647
• NCBI GeneID: 54892
• NCBI Accession #: NP_001268861.1
• NCBI GenBank Nucleotide #: NM_001281932.1
• UniProt Accession #: Q86XI2; Q7Z3J9; Q8WUG8; Q9BRX6; Q9H8S2; Q9H9K6; A4D228
• Molecular Weight: 132,196 Da
• NCBI Official Full Name: condensin-2 complex subunit G2 isoform a
• NCBI Official Synonym Full Names: non-SMC condensin II complex, subunit G2
• NCBI Official Symbol: NCAPG2
• NCBI Official Synonym Symbols: MTB; CAPG2; LUZP5; CAP-G2; hCAP-G2
• NCBI Protein Information: condensin-2 complex subunit G2
• UniProt Protein Name: Condensin-2 complex subunit G2
• Protein Family: Condensin-2 complex
• UniProt Gene Name: NCAPG2
• UniProt Synonym Gene Names: LUZP5; CAP-G2; hCAP-G2
• UniProt Entry Name: CNDG2_HUMAN

NCBI Description

This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Description

LUZP5: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 7q36.3

Cellular Component: nucleoplasm; membrane; nucleus

Molecular Function: protein binding; methylated histone residue binding

Biological Process: chromosome condensation; mitosis; cell division; mitotic cell cycle; inner cell mass cell proliferation