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FUK blocking peptide

FUK Blocking Peptide

Gene Names
FUK; 1110046B12Rik
Reactivity
Human, Mouse, Rat, Monkey
Applications
Blocking (BL)
Purity
>85%
Synonyms
FUK; FUK Blocking Peptide; L-fucose kinase; Fucokinase; FUK blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat, Monkey
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
1084
Applicable Applications for FUK blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for FUK blocking peptide
The peptide is used to block Anti-FUK Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
118,393 Da
NCBI Official Full Name
L-fucose kinase
NCBI Official Synonym Full Names
fucokinase
NCBI Official Symbol
FUK
NCBI Official Synonym Symbols
1110046B12Rik
NCBI Protein Information
L-fucose kinase
UniProt Protein Name
L-fucose kinase
Protein Family
UniProt Gene Name
FUK
UniProt Synonym Gene Names
Fucokinase
UniProt Entry Name
FUK_HUMAN

NCBI Description

The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]

Uniprot Description

FUK: Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. Belongs to the GHMP kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 2.7.1.52; Kinase, other

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytosol

Molecular Function: fucokinase activity

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Product Notes

The FUK fuk (Catalog #AAA8247843) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The FUK Blocking Peptide reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's FUK can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the FUK fuk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FUK, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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