GPRC5B blocking peptide

GPRC5B Blocking Peptide

Cat. Num. AAA824249

• Gene Names: GPRC5B; RAIG2; RAIG-2
• Reactivity: Human, Monkey
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: GPRC5B; GPRC5B Blocking Peptide; RAIG2; G-protein coupled receptor family C group 5 member B; A-69G12.1; Retinoic acid-induced gene 2 protein; RAIG-2; GPRC5B blocking peptide

• Host: Synthetic
• Reactivity: Human, Monkey
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 403

• Applicable Applications for GPRC5B blocking peptide: Blocking (BL)
• Application Notes: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for GPRC5B blocking peptide

The peptide is used to block Anti-GPRC5B Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 7706451
• NCBI GeneID: 51704
• NCBI Accession #: NP_057319.1
• NCBI GenBank Nucleotide #: NM_016235.1
• UniProt Accession #: Q9NZH0; O75205; Q8NBZ8; D2DFB0
• Molecular Weight: 44,933 Da
• NCBI Official Full Name: G-protein coupled receptor family C group 5 member B
• NCBI Official Synonym Full Names: G protein-coupled receptor, class C, group 5, member B
• NCBI Official Symbol: GPRC5B
• NCBI Official Synonym Symbols: RAIG2; RAIG-2
• NCBI Protein Information: G-protein coupled receptor family C group 5 member B; A-69G12.1; retinoic acid-induced gene 2 protein; retinoic acid responsive gene protein; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 5, member B
• UniProt Protein Name: G-protein coupled receptor family C group 5 member B
• Protein Family: G-protein coupled receptor family
• UniProt Gene Name: GPRC5B
• UniProt Synonym Gene Names: RAIG2; RAIG-2
• UniProt Entry Name: GPC5B_HUMAN

NCBI Description

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. [provided by RefSeq, Jul 2008]

Uniprot Description

GPRC5B: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 3; Receptor, GPCR

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: extracellular space; cytoplasmic vesicle membrane; cell surface; intracellular membrane-bound organelle; plasma membrane; nucleolus; integral to membrane; nucleus; lipid raft

Molecular Function: G-protein coupled receptor activity; G-protein-coupled receptor binding; protein kinase activator activity; protein kinase binding

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; locomotory behavior; positive regulation of neuron differentiation; glucose homeostasis; positive regulation of inflammatory response