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ZP1 blocking peptide

ZP1 Blocking Peptide

Gene Names
ZP1; OOMD; OOMD1; HEL163
Reactivity
Human
Applications
Blocking (BL)
Purity
>85%
Synonyms
ZP1; ZP1 Blocking Peptide; Zona pellucida sperm-binding protein 1; Zona pellucida glycoprotein 1; Zp-1; ZP1 blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human
Purity/Purification
>85%
Form/Format
Lyophilized Powder
Sequence Length
638
Applicable Applications for ZP1 blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for ZP1 blocking peptide
The peptide is used to block Anti-ZP1 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
70,049 Da
NCBI Official Full Name
Zona pellucida sperm-binding protein 1
NCBI Official Synonym Full Names
zona pellucida glycoprotein 1
NCBI Official Symbol
ZP1
NCBI Official Synonym Symbols
OOMD; OOMD1; HEL163
NCBI Protein Information
zona pellucida sperm-binding protein 1
UniProt Protein Name
Zona pellucida sperm-binding protein 1
UniProt Gene Name
ZP1
UniProt Synonym Gene Names
Zp-1
UniProt Entry Name
ZP1_HUMAN

NCBI Description

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014]

Uniprot Description

ZP1: The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. Belongs to the ZP domain family. ZPB subfamily.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: extracellular region; Golgi apparatus; integral to membrane; plasma membrane; proteinaceous extracellular matrix; secretory granule

Biological Process: binding of sperm to zona pellucida; multicellular organism reproduction; single fertilization

Disease: Oocyte Maturation Defect

Research Articles on ZP1

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Product Notes

The ZP1 zp1 (Catalog #AAA8243351) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The ZP1 Blocking Peptide reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZP1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the ZP1 zp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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