hnRNP H Blocking Peptide | HNRNPH1 blocking peptide

hnRNP H Blocking Peptide

Cat. Num. AAA824297

• Gene Names: HNRNPH1; HNRPH; HNRPH1; hnRNPH
• Reactivity: Human, Bovine, Chicken
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: hnRNP H; hnRNP H Blocking Peptide; HNRNPH1; HNRPH; HNRPH1; Heterogeneous nuclear ribonucleoprotein H; HNRNPH2; FTP3; HNRPH2; Heterogeneous nuclear ribonucleoprotein H2; hnRNP H2; FTP-3; Heterogeneous nuclear ribonucleoprotein H'; hnRNP H'; HNRNPH1 blocking peptide

• Host: Synthetic
• Reactivity: Human, Bovine, Chicken
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 449

• Applicable Applications for HNRNPH1 blocking peptide: Blocking (BL)
• Application Notes: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for HNRNPH1 blocking peptide

The peptide is used to block Anti-hnRNP H Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 381342476
• NCBI GeneID: 3187
• NCBI Accession #: NP_001244222.1
• NCBI GenBank Nucleotide #: NM_001257293.1
• UniProt Accession #: P31943; Q6IBM4; B3KW86; D3DWQ2
• Molecular Weight: 49,229 Da
• NCBI Official Full Name: heterogeneous nuclear ribonucleoprotein H
• NCBI Official Synonym Full Names: heterogeneous nuclear ribonucleoprotein H1 (H)
• NCBI Official Symbol: HNRNPH1
• NCBI Official Synonym Symbols: HNRPH; HNRPH1; hnRNPH
• NCBI Protein Information: heterogeneous nuclear ribonucleoprotein H
• UniProt Protein Name: Heterogeneous nuclear ribonucleoprotein H
• Protein Family: Heterogeneous nuclear ribonucleoprotein
• UniProt Gene Name: HNRNPH1
• UniProt Synonym Gene Names: HNRPH; HNRPH1; hnRNP H
• UniProt Entry Name: HNRH1_HUMAN

NCBI Description

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]

Uniprot Description

hnRNP H1: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).

Protein type: RNA-binding; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: nucleoplasm; membrane; nucleus

Molecular Function: protein binding; RNA binding; nucleotide binding; poly(U) binding

Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; regulation of RNA splicing; RNA splicing; gene expression