Cathepsin H Blocking Peptide | CTSH blocking peptide

Cathepsin H Blocking Peptide

Cat. Num. AAA8309007

• Gene Names: CTSH; CPSB; ACC-4; ACC-5; minichain
• Reactivity: Human
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: Cathepsin H; Cathepsin H Blocking Peptide; CPSB; Pro-cathepsin H; CTSH blocking peptide

• Host: Synthetic
• Reactivity: Human
• Purity/Purification: >85%
• Form/Format: Lyophilized Powder

• Applicable Applications for CTSH blocking peptide: Blocking (BL)
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Preparation and Storage: Store at -20 degree C for one year.

Related Product Information for CTSH blocking peptide

The peptide is used to block Anti-Cathepsin H Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 23110955
• NCBI GeneID: 1512
• NCBI Accession #: NP_004381.2
• NCBI GenBank Nucleotide #: NM_004390.3
• UniProt Accession #: P09668; Q96NY6; Q9BUM7; B2RBK0
• Molecular Weight: 160,000
• NCBI Official Full Name: pro-cathepsin H preproprotein
• NCBI Official Synonym Full Names: cathepsin H
• NCBI Official Symbol: CTSH
• NCBI Official Synonym Symbols: CPSB; ACC-4; ACC-5; minichain
• NCBI Protein Information: pro-cathepsin H; aleurain; cathepsin B3; cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase
• UniProt Protein Name: Pro-cathepsin H
• Protein Family: Pro-cathepsin
• UniProt Gene Name: CTSH
• UniProt Synonym Gene Names: CPSB
• UniProt Entry Name: CATH_HUMAN

NCBI Description

The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq, Mar 2010]

Uniprot Description

CTSH: Important for the overall degradation of proteins in lysosomes. Belongs to the peptidase C1 family.

Protein type: EC 3.4.22.16; Protease

Chromosomal Location of Human Ortholog: 15q25.1

Cellular Component: extracellular space; lysosome; acrosome; outer dense fiber; cytosol

Molecular Function: peptidase activity; protein binding; protein self-association; HLA-A specific activating MHC class I receptor activity; serine-type endopeptidase activity; cysteine-type endopeptidase activity; endopeptidase activity; protein complex binding; caspase activator activity; aminopeptidase activity; kininogen binding; cysteine-type peptidase activity

Biological Process: caspase activation; adaptive immune response; response to retinoic acid; protein destabilization; membrane protein proteolysis; proteolysis; antigen processing and presentation; positive regulation of angiogenesis; positive regulation of cell proliferation; zymogen activation; spermatogenesis; surfactant homeostasis; metanephros development; immune response-regulating signal transduction; positive regulation of cell migration; T cell mediated cytotoxicity; negative regulation of apoptosis