RPL3 blocking peptide

RPL3 Blocking Peptide

Cat. Num. AAA824146

• Gene Names: RPL3; L3; ASC-1; TARBP-B
• Reactivity: Human, Mouse, Rat, Bovine, Dog, Monkey
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: RPL3; RPL3 Blocking Peptide; 60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; TARBP-B; RPL3 blocking peptide

• Host: Synthetic
• Reactivity: Human, Mouse, Rat, Bovine, Dog, Monkey
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 403

• Applicable Applications for RPL3 blocking peptide: Blocking (BL)
• Application Notes: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for RPL3 blocking peptide

The peptide is used to block Anti-RPL3 Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 4506649
• NCBI GeneID: 6122
• NCBI Accession #: NP_000958.1
• NCBI GenBank Nucleotide #: NM_000967.3
• UniProt Accession #: P39023; Q15548; Q5I0G0; B2RDV9
• Molecular Weight: 46,109 Da
• NCBI Official Full Name: 60S ribosomal protein L3 isoform a
• NCBI Official Synonym Full Names: ribosomal protein L3
• NCBI Official Symbol: RPL3
• NCBI Official Synonym Symbols: L3; ASC-1; TARBP-B
• NCBI Protein Information: 60S ribosomal protein L3; hypothetical protein; HIV-1 TAR RNA-binding protein B; ribosomal protein L3, isoform a
• UniProt Protein Name: 60S ribosomal protein L3
• Protein Family: Ribosomal protein
• UniProt Gene Name: RPL3
• UniProt Synonym Gene Names: TARBP-B
• UniProt Entry Name: RL3_HUMAN

NCBI Description

Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Description

RPL3: The L3 protein is a component of the large subunit of cytoplasmic ribosomes. Belongs to the ribosomal protein L3P family.

Protein type: Translation; Nucleolus; Ribosomal

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: nucleoplasm; focal adhesion; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; viral reproduction; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression; viral infectious cycle; translational termination