Structure
(Structure of T8488.)
[2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide Biochemical
[2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide (MTSET Bromide)
Purity
~90%
Synonyms
[2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide; [2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide (MTSET Bromide); [2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide biochemical
Host
Synthetic
Purity/Purification
~90%
Form/Format
Supplied as a white solid.
CAS Number
91774-25-3
Molecular Formula
C6H16BrNO2S2
Atmosphere
Inert gas
Melting Point
151-158 degree C
Solubility
Methanol, Water
TLC Conditions
C18 (Reverse Phase); Acetic Acid: Isopropanol: Water; 3:2:1; Visualized with ninhydrin; Single spot Rf=0.65.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Moisture Sensitive.
Stability: Moisture sensitive
Stability: Moisture sensitive
Structure
(Structure of T8488.)
Structure
(Structure of T8488.)
Related Product Information for [2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide biochemical
Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.
At pH 7.5 and room temperature, MTSEA hydrolyzes with a half-life of about 15 minutes, MTSET hydrolyzes with a half-life of 10 minutes, and MTSES hydrolyzes with a half-life of 20 minutes. Routinely, one can use 2.5mM MTSEA, 1mM MTSET, or 10mM MTSES, applied for 1 to 5 minutes. (MTSET is 2.5 times as reactive with small sulfhydryl compounds as is MTSEA, and 10 times as reactive as MTSES). (Stauffer and Karlin, 1994; Karlin, personal communication).
For application to Xenopus Oocytes, dissolve the compounds in 115mM NaCl, 2.5mM KCl, 1.8mM MgCl2, 10mM Hepes, pH 7.5 with NaOH. MTS reagents decompose in buffer very quickly.
•DMSO is a good solvent for the MTS reagents which are not water soluble (i.e. the non-charged MTS reagents).
At pH 7.5 and room temperature, MTSEA hydrolyzes with a half-life of about 15 minutes, MTSET hydrolyzes with a half-life of 10 minutes, and MTSES hydrolyzes with a half-life of 20 minutes. Routinely, one can use 2.5mM MTSEA, 1mM MTSET, or 10mM MTSES, applied for 1 to 5 minutes. (MTSET is 2.5 times as reactive with small sulfhydryl compounds as is MTSEA, and 10 times as reactive as MTSES). (Stauffer and Karlin, 1994; Karlin, personal communication).
For application to Xenopus Oocytes, dissolve the compounds in 115mM NaCl, 2.5mM KCl, 1.8mM MgCl2, 10mM Hepes, pH 7.5 with NaOH. MTS reagents decompose in buffer very quickly.
•DMSO is a good solvent for the MTS reagents which are not water soluble (i.e. the non-charged MTS reagents).
Product Categories/Family for [2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide biochemical
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Product Notes
The [2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide (Catalog #AAA6056221) is a Biochemical produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "[2-(Trimethylammonium)ethyl] Methanethiosulfonate Bromide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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