EMR1 Blocking Peptide | ADGRE1 blocking peptide

EMR1 Blocking Peptide

Cat. Num. AAA8309508

• Gene Names: EMR1; TM7LN3
• Reactivity: Human, Rat
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: EMR1; EMR1 Blocking Peptide; TM7LN3; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-like module receptor 1; EMR1 hormone receptor; Adhesion G protein-coupled receptor E1; ADGRE1 blocking peptide

• Host: Synthetic
• Reactivity: Human, Rat
• Purity/Purification: >85%
• Form/Format: Lyophilized Powder

• Applicable Applications for ADGRE1 blocking peptide: Blocking (BL)
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Preparation and Storage: Store at -20 degree C for one year.

Related Product Information for ADGRE1 blocking peptide

The peptide is used to block Anti-EMR1 Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 372266078
• NCBI GeneID: 2015
• NCBI Accession #: NP_001243181.1
• NCBI GenBank Nucleotide #: NM_001256252.1
• UniProt Accession #: Q14246; Q5Y4N8
• Molecular Weight: 97,683 Da
• NCBI Official Full Name: EGF-like module-containing mucin-like hormone receptor-like 1 isoform 2
• NCBI Official Synonym Full Names: egf-like module containing, mucin-like, hormone receptor-like 1
• NCBI Official Symbol: EMR1
• NCBI Official Synonym Symbols: TM7LN3
• NCBI Protein Information: EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EGF-like module receptor 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1
• UniProt Protein Name: EGF-like module-containing mucin-like hormone receptor-like 1
• Protein Family: Adhesion G protein-coupled receptor
• UniProt Gene Name: EMR1
• UniProt Synonym Gene Names: TM7LN3
• UniProt Entry Name: EMR1_HUMAN

NCBI Description

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion