SYNCI Blocking Peptide | SYNC blocking peptide

SYNCI Antibody (N-term) Blocking peptide

• Gene Names: SYNC; SYNC1; SYNCOILIN
• Synonyms: SYNCI; SYNCI Antibody (N-term) Blocking peptide; Syncoilin; Syncoilin intermediate filament 1; Syncoilin-1; SYNC; SYNC1; SYNC blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 482

• Cellular Location: Cytoplasm, perinuclear region. Note: In skeletal muscle, colocalizes with DES and DTNA, and is localized at the myotendinous and neuromuscular junctions, sarcolemma and Z-lines In myotubes, detected in a punctate cytoplasmic pattern (By similarity).
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SYNC blocking peptide

Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 300669677
• NCBI GeneID: 81493
• UniProt Accession #: Q9H7C4; B4DNK8; B4DY58; C9IY41
• Molecular Weight: 54,947 Da
• NCBI Official Full Name: Syncoilin
• NCBI Official Synonym Full Names: syncoilin, intermediate filament protein
• NCBI Official Symbol: SYNC
• NCBI Official Synonym Symbols: SYNC1; SYNCOILIN
• NCBI Protein Information: syncoilin
• UniProt Protein Name: Syncoilin
• Protein Family: Syncoilin
• UniProt Gene Name: SYNC
• UniProt Synonym Gene Names: SYNC1
• UniProt Entry Name: SYNCI_HUMAN

NCBI Description

This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Uniprot Description

SYNC1: a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Chromosomal Location of Human Ortholog: 1p35.1