SDS-PAGE
SUSD4 / Sushi domain-containing 4 Recombinant Protein | SUSD4 recombinant protein
Recombinant Human SUSD4 / Sushi domain-containing protein 4 Protein (Fc tag)
Gene Names
SUSD4; PRO222
Purity
> 85 % as determined by SDS-PAGE
Synonyms
SUSD4 / Sushi domain-containing 4; Recombinant Human SUSD4 / Sushi domain-containing protein 4 Protein (Fc tag); SUSD4; SUSD4 recombinant protein
Host
Human Cells
Purity/Purification
> 85 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
290
Application Notes
The recombinant human SUSD4/mFc is a disulfide-linked homodimer. The reduced monomer comprises 483 amino acids and has a predicted molecular mass of 53.8 kDa. The apparent molecular mass of the protein is approximately 67 in SDS-PAGE under reducing conditions.
Predicted N Terminal
Phe 42
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for SUSD4 recombinant protein
Background: SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical pathway of complement activation at the C3 convertase step. SUSD4 deficiency may cause autism or Fryns syndrome, both of which are genetic diseases with severe abnormal neurological development and/or functions.
Description: A DNA sequence encoding the human SUSD4 (Q5VX71-3) (Met1-Phe290) was fused with Fc region of mouse IgG at the C-terminus.
Description: A DNA sequence encoding the human SUSD4 (Q5VX71-3) (Met1-Phe290) was fused with Fc region of mouse IgG at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,094 Da
NCBI Official Full Name
sushi domain-containing protein 4 isoform b
NCBI Official Synonym Full Names
sushi domain containing 4
NCBI Official Symbol
SUSD4
NCBI Official Synonym Symbols
PRO222
NCBI Protein Information
sushi domain-containing protein 4
UniProt Protein Name
Sushi domain-containing protein 4
Protein Family
UniProt Gene Name
SUSD4
Uniprot Description
SUSD4: 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q41
Biological Process: regulation of complement activation
Research Articles on SUSD4
Similar Products
Product Notes
The SUSD4 susd4 (Catalog #AAA2545305) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human SUSD4/mFc is a disulfide-linked homodimer. The reduced monomer comprises 483 amino acids and has a predicted molecular mass of 53.8 kDa. The apparent molecular mass of the protein is approximately 67 in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the SUSD4 susd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUSD4 / Sushi domain-containing 4, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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