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Munc18c/STXBP3 Recombinant Protein | STXBP3 recombinant protein
Munc18c/STXBP3 Protein, Human, Recombinant (His & GST Tag)
Gene Names
STXBP3; PSP; MUNC18C; UNC-18C; MUNC18-3
Purity
>82% as determined by SDS-PAGE
Synonyms
Munc18c/STXBP3; Munc18c/STXBP3 Protein; Human; Recombinant (His & GST Tag); Human STXBP3/UNC-18C Protein (His & GST Tag); MUNC18-3 Protein; MUNC18C Protein; PSP Protein; UNC-18C Protein; syntaxin binding protein 3; STXBP3 recombinant protein
Host
Baculovirus-Insect Cells
Purity/Purification
>82% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 20mM Tris, 500mM NaCl, pH8.5, 10% glycerol. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Glu592
Species
Human
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Met
Tag
N-GST & His
Protein Construction
A DNA sequence encoding the human STXBP3 (O00186-1)(Met 1-Glu 592) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for STXBP3 recombinant protein
Background: Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STXBP3 participates in the consolidation and secretion of secondary and tertiary granules. STXBP3 contains one SEC1 domain. Phosphorylation at Ser129 may stimulate granule release. Human STXBP3 shares 9% aa identity with mouse STXBP3. STXBP3 interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion. Interacts with STX4.
References
Kidd,M. et al., 2008, Am J Physiol Gastrointest Liver Physiol. 295 (2): G260-72. Macedo,C. et al., 2008, Mol Cell Biochem. 318 (1-2): 63-71.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
67,764 Da
NCBI Official Full Name
syntaxin-binding protein 3
NCBI Official Synonym Full Names
syntaxin binding protein 3
NCBI Official Symbol
STXBP3
NCBI Official Synonym Symbols
PSP; MUNC18C; UNC-18C; MUNC18-3
NCBI Protein Information
syntaxin-binding protein 3
UniProt Protein Name
Syntaxin-binding protein 3
Protein Family
UniProt Gene Name
STXBP3
UniProt Synonym Gene Names
PSP; Unc18-3; Unc-18C
UniProt Entry Name
STXB3_HUMAN
Research Articles on STXBP3
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Product Notes
The STXBP3 stxbp3 (Catalog #AAA8120980) is a Recombinant Protein produced from Baculovirus-Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Glu59 2. It is sometimes possible for the material contained within the vial of "Munc18c/STXBP3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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