Mouse Signal transducer and activator of transcription 5B ELISA Kit | Stat5b elisa kit

Mouse Signal transducer and activator of transcription 5B ELISA Kit

Cat. Num. AAA2880836

• Reactivity: Mouse
• Synonyms: Signal transducer and activator of transcription 5B; Mouse Signal transducer and activator of transcription 5B ELISA Kit; Stat5b; Stat5b elisa kit

• Reactivity: Mouse
• Sequence Length: 786

• Assay Type: Sandwich
• Detection Range: 1.56-100 ng/mL
• Sensitivity: 0.78 ng/mL
• Intra-Assay CV: <=6.2%
• Inter-Assay CV: <=8.7%
• Recovery: 85%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 165932368
• NCBI GeneID: 20851
• NCBI Accession #: NP_001107035.1
• NCBI GenBank Nucleotide #: NM_001113563.1
• UniProt Accession #: P42232; Q541Q5; Q60804; Q8K3Q1; Q9JKM1; Q9R0X8; A2A5D5
• Molecular Weight: 90,002 Da
• NCBI Official Full Name: signal transducer and activator of transcription 5B
• NCBI Official Synonym Full Names: signal transducer and activator of transcription 5B
• NCBI Official Symbol: Stat5b
• NCBI Protein Information: signal transducer and activator of transcription 5B
• UniProt Protein Name: Signal transducer and activator of transcription 5B
• Protein Family: Signal transducer and activator of transcription
• UniProt Gene Name: Stat5b
• UniProt Entry Name: STA5B_MOUSE

Uniprot Description

STAT5B: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases triggered by cytokines including IL2, IL3, GM-CSF, and various growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. Forms homo- or heterodimers that translocate into the nucleus where they regulate transcription.

Protein type: Transcription factor; DNA-binding; Oncoprotein

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: chromatin binding; DNA binding; double-stranded DNA binding; glucocorticoid receptor binding; protein binding; protein dimerization activity; protein phosphatase binding; sequence-specific DNA binding; signal transducer activity; transcription factor activity

Biological Process: 2-oxoglutarate metabolic process; acute-phase response; allantoin metabolic process; cellular response to hormone stimulus; citrate metabolic process; creatine metabolic process; creatinine metabolic process; cytokine and chemokine mediated signaling pathway; development of secondary female sexual characteristics; development of secondary male sexual characteristics; fatty acid metabolic process; female pregnancy; isoleucine metabolic process; JAK-STAT cascade; lactation; liver development; luteinization; natural killer cell differentiation; negative regulation of apoptosis; negative regulation of erythrocyte differentiation; oxaloacetate metabolic process; Peyer's patch development; positive regulation of activated T cell proliferation; positive regulation of B cell differentiation; positive regulation of cell motility; positive regulation of cell proliferation; positive regulation of gamma-delta T cell differentiation; positive regulation of inflammatory response; positive regulation of interleukin-2 biosynthetic process; positive regulation of lymphocyte differentiation; positive regulation of mitotic cell cycle; positive regulation of multicellular organism growth; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell proliferation; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; progesterone metabolic process; regulation of cell adhesion; regulation of epithelial cell differentiation; regulation of multicellular organism growth; regulation of steroid metabolic process; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to estradiol stimulus; response to lipopolysaccharide; response to peptide hormone stimulus; sequestering of lipid; sex differentiation; signal transduction; succinate metabolic process; T cell differentiation in the thymus; T cell homeostasis; taurine metabolic process; transcription from RNA polymerase II promoter; transcription, DNA-dependent; valine metabolic process