Serine/arginine-rich splicing factor 2 (Srsf2) Recombinant Protein | Srsf2 recombinant protein
Recombinant Mouse Serine/arginine-rich splicing factor 2 (Srsf2)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. [provided by RefSeq, Sep 2010]
Uniprot Description
Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA (). Can bind to the myelin basic protein (MBP) gene MB3 regulatory region and increase transcription of the mbp promoter in cells derived from the CNS. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment ().
Research Articles on Srsf2
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Product Notes
The Srsf2 srsf2 (Catalog #AAA1390889) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-221, full length protein. The amino acid sequence is listed below: SYGRPPPDVE GMTSLKVDNL TYRTSPDTLR RVFEKYGRVG DVYIPRDRYT KESRGFAFVR FHDKRDAEDA MDAMDGAVLD GRELRVQMAR YGRPPDSHHS RRGPPPRRYG GGGYGRRSRS PRRRRRSRSR SRSRSRSRSR SRYSRSKSRS RTRSRSRSTS KSRSARRSKS KSSSVSRSRS RSRSRSRSRS PPPVSKRESK SRSRSKSPPK SPEEEGAVSS. It is sometimes possible for the material contained within the vial of "Serine/arginine-rich splicing factor 2 (Srsf2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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