Rat Serine/arginine-rich splicing factor 2 ELISA Kit | Srsf2 elisa kit
Rat Serine/arginine-rich splicing factor 2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SFRS2: Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre- mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment. Belongs to the splicing factor SR family.
Protein type: RNA splicing; RNA processing; Spliceosome
Cellular Component: cytoplasm; nuclear speck; nucleus; PML body; spliceosome
Molecular Function: nucleotide binding
Biological Process: mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome; RNA splicing
Research Articles on Srsf2
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Product Notes
The Rat Srsf2 srsf2 (Catalog #AAA2884651) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884651 ELISA Kit recognizes Rat Srsf2. It is sometimes possible for the material contained within the vial of "Serine/arginine-rich splicing factor 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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