SDS-PAGE
Signal recognition particle 14 kDa Recombinant Protein | SRP14 recombinant protein
Recombinant Human Signal recognition particle 14 kDa protein
Gene Names
SRP14; ALURBP
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Signal recognition particle 14 kDa; Recombinant Human Signal recognition particle 14 kDa protein; 18 kDa Alu RNA-binding protein; SRP14 recombinant protein
Host
E Coli
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
2-108aa; Partial
Sequence
VLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKA
Sequence Length
136
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for SRP14 recombinant protein
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Product Categories/Family for SRP14 recombinant protein
References
The SRP9/14 subunit of the signal recognition particle (SRP)
is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs.Bovia F., Fornallaz M., Leffers H., Strub K.Mol. Biol. Cell 6:471-484(1995)
A human Alu RNA-binding protein whose expression is associated with accumulation of small cytoplasmic Alu RNA.Chang D.-Y., Nelson B., Bilyeu T., Hsu K., Darlington G.J., Maraia R.J.Mol. Cell. Biol. 14:3949-3959(1994)
A novel gene encoding signal recognition particle 14kD is upregulated in the acute morphine dependent SH-SY5Y cells.Wang H., Gao X., Huang Y., Han J.Human protein factory for converting the transcriptome into an in vitro-expressed proteome.Goshima N., Kawamura Y., Fukumoto A., Miura A., Honma R., Satoh R., Wakamatsu A., Yamamoto J., Kimura K., Nishikawa T., Andoh T., Iida Y., Ishikawa K., Ito E., Kagawa N., Kaminaga C., Kanehori K., Kawakami B., Kenmochi K., Kimura R., Kobayashi M., Kuroita T., Kuwayama H., Maruyama Y., Matsuo K., Minami K., Mitsubori M., Mori M., Morishita R., Murase A., Nishikawa A., Nishikawa S., Okamoto T., Sakagami N., Sakamoto Y., Sasaki Y., Seki T., Sono S., Sugiyama A., Sumiya T., Takayama T., Takayama Y., Takeda H., Togashi T., Yahata K., Yamada H., Yanagisawa Y., Endo Y., Imamoto F., Kisu Y., Tanaka S., Isogai T., Imai J., Watanabe S., Nomura N.Nat. Methods 5:1011-1017(2008)
Analysis of the DNA sequence and duplication history of human chromosome 15.Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.Nature 440:671-675(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39.2 kDa
NCBI Official Full Name
signal recognition particle 14 kDa protein isoform 1
NCBI Official Synonym Full Names
signal recognition particle 14kDa
NCBI Official Symbol
SRP14
NCBI Official Synonym Symbols
ALURBP
NCBI Protein Information
signal recognition particle 14 kDa protein
UniProt Protein Name
Signal recognition particle 14 kDa protein
Protein Family
UniProt Gene Name
SRP14
UniProt Synonym Gene Names
SRP14
UniProt Entry Name
SRP14_HUMAN
Uniprot Description
SRP14: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Belongs to the SRP14 family.
Protein type: Translation; RNA-binding
Chromosomal Location of Human Ortholog: 15q22
Cellular Component: cytoplasm; cytosol; nucleus; signal recognition particle, endoplasmic reticulum targeting
Molecular Function: 7S RNA binding; endoplasmic reticulum signal peptide binding; protein binding; RNA binding
Biological Process: cellular protein metabolic process; cotranslational protein targeting to membrane; gene expression; protein targeting to ER; response to drug; SRP-dependent cotranslational protein targeting to membrane; translation
Research Articles on SRP14
Similar Products
Product Notes
The SRP14 srp14 (Catalog #AAA1265367) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-108aa; Partial. The amino acid sequence is listed below: VLLESEQFLT ELTRLFQKCR TSGSVYITLK KYDGRTKPIP KKGTVEGFEP ADNKCLLRAT DGKKKISTVV SSKEVNKFQM AYSNLLRANM DGLKKRDKKN KTKKTKA. It is sometimes possible for the material contained within the vial of "Signal recognition particle 14 kDa, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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