SPECC1 Blocking Peptide | SPECC1L blocking peptide
SPECC1 Antibody (Center) Blocking peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
Uniprot Description
SPECC1L: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. Defects in SPECC1L are the cause of facial clefting oblique type 1 (OBLFC1). A rare form of facial clefting. A facial cleft is any of the fissures between the embryonic prominences that normally unite to form the face. Belongs to the cytospin-A family.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 22q11.23
Biological Process: cell adhesion
Disease: Facial Clefting, Oblique, 1; Opitz Gbbb Syndrome, Type Ii
Research Articles on SPECC1L
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Product Notes
The SPECC1L specc1l (Catalog #AAA9218881) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SPECC1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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