Sorting nexin-33 (SNX33) Recombinant Protein | SNX33 recombinant protein

Recombinant Human Sorting nexin-33 (SNX33)

Cat. Num. AAA1434467

• Gene Names: SNX33; SNX30; SH3PX3; SH3PXD3C
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Sorting nexin-33 (SNX33); Recombinant Human Sorting nexin-33 (SNX33); SNX33 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-574, Full length protein
• Sequence: MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDWDDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGRNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL
• Sequence Length: 574

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 970259828
• NCBI GeneID: 257364
• NCBI Accession #: NP_001305075.1
• NCBI GenBank Nucleotide #: NM_001318146.1
• UniProt Accession #: Q8WV41; B1NM17
• Molecular Weight: 65,265 Da
• NCBI Official Full Name: sorting nexin-33 isoform 2
• NCBI Official Synonym Full Names: sorting nexin 33
• NCBI Official Symbol: SNX33
• NCBI Official Synonym Symbols: SNX30; SH3PX3; SH3PXD3C
• NCBI Protein Information: sorting nexin-33
• UniProt Protein Name: Sorting nexin-33
• Protein Family: Sorting nexin
• UniProt Gene Name: SNX33
• UniProt Synonym Gene Names: SH3PX3; SH3PXD3C; SNX30

NCBI Description

The protein encoded by this gene is involved in cytoskeletal reorganization, vesicle trafficking, endocytosis, and mitosis. The encoded protein is essential for the creation of the cleavage furrow during mitosis and for completion of mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

Uniprot Description

Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes.