Human SET and MYND domain containing 3 ELISA Kit | SMYD3 elisa kit

Human SET and MYND domain-containing protein 3, SMYD3 ELISA Kit

Cat. Num. AAA9337146

• Gene Names: SMYD3; KMT3E; ZMYND1; ZNFN3A1; bA74P14.1
• Reactivity: Human
• Synonyms: SET and MYND domain containing 3; Human SET and MYND domain-containing protein 3; SMYD3 ELISA Kit; Human SET and MYND domain-containing protein 3 (SMYD3) ELISA kit; FLJ21080; MGC104324; ZMYND1; ZNFN3A1; bA74P14.1; bA74P14.1 (novel protein) ; zinc finger protein; subfamily 3A (MYND domain containing); 1; zinc finger; MYND domain containing 1; SMYD3 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 31.2 pg/ml - 1000 pg/ml
• Sensitivity: 5.0 pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SMYD3 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of SMYD3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 267844824
• NCBI GeneID: 64754
• NCBI Accession #: NP_001161212.1
• NCBI GenBank Nucleotide #: NM_001167740.1
• UniProt Accession #: Q9H7B4; Q86TL8; Q8N5Z6; Q96AI5; A8K0P0; B1AN38
• Molecular Weight: 49,097 Da
• NCBI Official Full Name: histone-lysine N-methyltransferase SMYD3 isoform 1
• NCBI Official Synonym Full Names: SET and MYND domain containing 3
• NCBI Official Symbol: SMYD3
• NCBI Official Synonym Symbols: KMT3E; ZMYND1; ZNFN3A1; bA74P14.1
• NCBI Protein Information: histone-lysine N-methyltransferase SMYD3; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; SET and MYND domain-containing protein 3; zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1
• UniProt Protein Name: Histone-lysine N-methyltransferase SMYD3
• Protein Family: Histone-lysine N-methyltransferase
• UniProt Gene Name: SMYD3
• UniProt Synonym Gene Names: ZMYND1; ZNFN3A1
• UniProt Entry Name: SMYD3_HUMAN

NCBI Description

This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

SMYD3: Histone methyltransferase. Specifically methylates 'Lys- 4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase, protein lysine; Methyltransferase; EC 2.1.1.43

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: metal ion binding; histone-lysine N-methyltransferase activity

Biological Process: nucleosome assembly; establishment of protein localization; establishment and/or maintenance of chromatin architecture; myotube cell development; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation