N-lysine methyltransferase SMYD2 (SMYD2) Recombinant Protein | SMYD2 recombinant protein
Recombinant Pig N-lysine methyltransferase SMYD2 (SMYD2)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
N-lysine methyltransferase SMYD2 (SMYD2); Recombinant Pig N-lysine methyltransferase SMYD2 (SMYD2); SMYD2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-433, Full length protein
Sequence
MRAEGDGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEFCFARKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKRDLIQSDIAALHHFYSKHLEFPDSDSLVVLFAQVNCNGFTIEDEELSHLGSXIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLNDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSCVFEDSNVYMLHMMYQAMGVCLYMQDWEGALRYGQKIIQPYSKHYPLYSLNVASMWLKLGRLYMGLENKAAGERALRKAIAIMEVAHGKDHPYISEIKQEIESH
Sequence Length
433
Species
Sus scrofa (Pig)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,870 Da
NCBI Official Full Name
N-lysine methyltransferase SMYD2
NCBI Official Symbol
SMYD2
NCBI Protein Information
N-lysine methyltransferase SMYD2
UniProt Protein Name
N-lysine methyltransferase SMYD2
Protein Family
UniProt Gene Name
SMYD2
Uniprot Description
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860' ().
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Product Notes
The SMYD2 smyd2 (Catalog #AAA1216630) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-433, Full length protein. The amino acid sequence is listed below: MRAEGDGGLE RFCSPGKGRG LRALQPFQVG DLLFSCPAYA YVLTVNERGN HCEFCFARKE GLSKCGRCKQ AFYCNVECQK EDWPMHKLEC SPMVVFGENW NPSETVRLTA RILAKQKIHP ERTPSEKLLA VKEFESHLDK LDNEKRDLIQ SDIAALHHFY SKHLEFPDSD SLVVLFAQVN CNGFTIEDEE LSHLGSXIFP DVALMNHSCC PNVIVTYKGT LAEVRAVQEI HPGEEVFTSY IDLLYPTEDR NDRLRDSYFF TCECQECTTK DKDKAKVEIR KLNDPPKAEA IRDMVRYARN VIEEFRRAKH YKSPSELLEI CELSQEKMSC VFEDSNVYML HMMYQAMGVC LYMQDWEGAL RYGQKIIQPY SKHYPLYSLN VASMWLKLGR LYMGLENKAA GERALRKAIA IMEVAHGKDH PYISEIKQEI ESH. It is sometimes possible for the material contained within the vial of "N-lysine methyltransferase SMYD2 (SMYD2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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