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Chromogranin-A/Chga protein Active Protein | Chga active protein
Recombinant Mouse Chromogranin-A/Chga protein (His Tag)
Gene Names
Chga; ChrA
Purity
>90% as determined by reducing SDS-PAGE
Synonyms
Chromogranin-A/Chga protein; Recombinant Mouse Chromogranin-A/Chga protein (His Tag); beta Granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHG A; Chga; chromofungin; Chromogranin A; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; CMGA; ER-37; Pancreastatin; Parastatin; Parathyroid secretory protein 1; Pituitary secretory protein I; Secretory protein I; SP I; SP-I; SP1; SPI; Vasostatin; Vasostatin I; Vasostatin II; Chga active protein
Host
E Coli
Purity/Purification
>90% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4
Sequence
457Ile-717Leu
Species
Mouse
Tag
N/C-His
Protein Construction
A DNA sequence encoding theMouse Chromogranin-A/Chga(P26339)(457Ile-717Leu) was expressed with a polyhistidine tag at the N-terminus.
Activity
Immunogen (E-AB-40339)
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.
This product is provided as lyophilized powder which is shipped with ice packs.
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SDS-Page
Related Product Information for Chga active protein
Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation. Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,789 Da
NCBI Official Full Name
chromogranin-A
NCBI Official Synonym Full Names
chromogranin A
NCBI Official Symbol
Chga
NCBI Official Synonym Symbols
ChrA
NCBI Protein Information
chromogranin-A; cgA
UniProt Protein Name
Chromogranin-A
Protein Family
UniProt Gene Name
Chga
UniProt Entry Name
CMGA_MOUSE
Uniprot Description
Function: Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
Subcellular location: Secreted. Note: Neuroendocrine and endocrine secretory granules.
Post-translational modification: CgA is O-glycosylated.
Miscellaneous: Binds calcium with a low-affinity.
Sequence similarities: Belongs to the chromogranin/secretogranin protein family.
Research Articles on Chga
Similar Products
Product Notes
The Chga chga (Catalog #AAA2569376) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: 457Ile-717 Leu. It is sometimes possible for the material contained within the vial of "Chromogranin-A/Chga protein, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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