SDS-Page
(Recombinant SMYD1 protein gel. SMYD1 protein was run on an SDS-PAGE gel and stained with Coomassie blue.)
SMYD1 recombinant protein
Recombinant SMYD1 protein
Gene Names
SMYD1; BOP; KMT3D; ZMYND18; ZMYND22
Purity
The recombinant protein is >85% pure by SDS-PAGE.
Synonyms
SMYD1; Recombinant SMYD1 protein; BOP; KMT3D; ZMYND18; ZMYND22; SMYD1 recombinant protein
Host
Baculovirus
Purity/Purification
The recombinant protein is >85% pure by SDS-PAGE.
Form/Format
Full length recombinant SMYD1 protein expressed in Sf9 cells and supplied in 25mM HEPES pH7.5, 120mM NaCl, 0.2mg/ml 3X DYKDDDDK peptide and 5% glycerol.
Protein Species
Human
Tag
DYKDDDDK-Tag
Notes
Recombinant SMYD1 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. Specific Activity: Not known. May methylate non-histone substrates.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant SMYD1 protein gel. SMYD1 protein was run on an SDS-PAGE gel and stained with Coomassie blue.)
SDS-Page
(Recombinant SMYD1 protein gel. SMYD1 protein was run on an SDS-PAGE gel and stained with Coomassie blue.)
Related Product Information for SMYD1 recombinant protein
Short Description: Recombinant SMYD1 (accession number NP_938015.1) was expressed in Sf9 cells and contains an N-terminal DYKDDDDK tag with an observed molecular weight of 58.3 kDa. SET and MYND domain-containing protein 1 (Smyd1) is a member of the Smyd family of histone methyltransferases that possesses H3K4 methyltransferase activity. It has also been shown to act as a transcriptional repressor. Studies suggest that Smyd1 may play a critical role in cardiomyocyte differentiation and cardiac morphogenesis and that it also may have a function in skeletal muscle development. Recombinant Smyd1 can be used to study enzyme kinetics and perform inhibitor screening assays.
Background: SET and MYND domain-containing protein 1 (SMYD1) is a member of the SMYD family of histone methyltransferases that possesses H3K4 methyltransferase activity. It has also been shown to act as a transcriptional repressor. Studies suggest that SMYD1 may play a critical role in cardiomyocyte differentiation and cardiac morphogenesis and that it also may have a function in skeletal muscle development.
Background: SET and MYND domain-containing protein 1 (SMYD1) is a member of the SMYD family of histone methyltransferases that possesses H3K4 methyltransferase activity. It has also been shown to act as a transcriptional repressor. Studies suggest that SMYD1 may play a critical role in cardiomyocyte differentiation and cardiac morphogenesis and that it also may have a function in skeletal muscle development.
Product Categories/Family for SMYD1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56
NCBI Official Full Name
histone-lysine N-methyltransferase SMYD1 isoform 1
NCBI Official Synonym Full Names
SET and MYND domain containing 1
NCBI Official Symbol
SMYD1
NCBI Official Synonym Symbols
BOP; KMT3D; ZMYND18; ZMYND22
NCBI Protein Information
histone-lysine N-methyltransferase SMYD1
UniProt Protein Name
Histone-lysine N-methyltransferase SMYD1
Protein Family
UniProt Gene Name
SMYD1
UniProt Entry Name
SMYD1_HUMAN
Uniprot Description
SMYD1: Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Protein type: Methyltransferase, protein lysine; Transcription, coactivator/corepressor; EC 2.1.1.43
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; DNA binding; metal ion binding; histone-lysine N-methyltransferase activity; transcription corepressor activity
Biological Process: chromatin remodeling; transcription, DNA-dependent; heart development; negative regulation of transcription, DNA-dependent; positive regulation of myoblast differentiation
Research Articles on SMYD1
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Product Notes
The SMYD1 smyd1 (Catalog #AAA388123) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SMYD1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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