Mouse solute carrier family 2 (facilitated glucose transporter) , member 4 ELISA Kit | SLC2A4 elisa kit
Mouse Solute carrier family 2, facilitated glucose transporter member 4, SLC2A4 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
GLUT4: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Its surface expression is regulated by insulin. Has two internalization sequences, a dileucine repeat present in the C-terminus and a FxxY motif in the amino-terminal end. Associates with an intracellular tubulo-vesicular compartment under low plasma conditions. The binding of insulin to the insulin receptor (a typosine kinase) leads to the rapid translocation of GLUT4 to the cell surface, increasing cellular glucose transport activity. Its translocation to the plasma membrane is also stimulated by exercise, but independent from insulin signaling. This insulin-independent pathway may be regulated by AMPK.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Cellular Component: cell surface; cytoplasmic vesicle membrane; clathrin-coated vesicle; intracellular membrane-bound organelle; integral to plasma membrane; T-tubule; integral to membrane; endomembrane system; coated pit; vesicle membrane; cytosol; lipid raft; multivesicular body; trans-Golgi network transport vesicle; membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; endosome; sarcolemma; vesicle; external side of plasma membrane
Molecular Function: D-glucose transmembrane transporter activity; protein binding; transporter activity; insulin-responsive hydrogen:glucose symporter activity; glucose transmembrane transporter activity; transmembrane transporter activity; substrate-specific transmembrane transporter activity
Biological Process: amylopectin biosynthetic process; proton transport; cellular response to insulin stimulus; transport; carbohydrate transport; brown fat cell differentiation; glucose transport; glucose homeostasis; transmembrane transport
Research Articles on SLC2A4
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Product Notes
The Mouse SLC2A4 slc2a4 (Catalog #AAA9318113) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318113 ELISA Kit recognizes Mouse SLC2A4. It is sometimes possible for the material contained within the vial of "solute carrier family 2 (facilitated glucose transporter) , member 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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