Human solute carrier family 17 (sodium phosphate) , member 4 ELISA Kit | SLC17A4 elisa kit
Human Putative small intestine sodium-dependent phosphate transport protein, SLC17A4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]).[supplied by OMIM, Feb 2011]
Uniprot Description
SLC17A4: May be involved in actively transporting phosphate into cells via Na(+) cotransport. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 6p22.2
Cellular Component: membrane; integral to plasma membrane; apical plasma membrane
Molecular Function: sodium:phosphate symporter activity
Biological Process: sodium ion transport; phosphate metabolic process
Research Articles on SLC17A4
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Product Notes
The Human SLC17A4 slc17a4 (Catalog #AAA9325665) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325665 ELISA Kit recognizes Human SLC17A4. It is sometimes possible for the material contained within the vial of "solute carrier family 17 (sodium phosphate) , member 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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