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Immunofluorescence (IF) (Immunofluorescent analysis of Hela cells using MBS7004490 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human SLC17A4 Polyclonal Antibody | anti-SLC17A4 antibody

SLC17A4 Antibody

Gene Names
SLC17A4; KAIA2138
Reactivity
Human
Applications
ELISA, Immunofluorescence
Purity
>95%,Protein G purified
Synonyms
SLC17A4; Polyclonal Antibody; SLC17A4 Antibody; Probable small intestine urate exporter; Solute carrier family 17 member 4; anti-SLC17A4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
443
Applicable Applications for anti-SLC17A4 antibody
ELISA (EIA), Immunofluorescence (IF)
Immunogen
Recombinant human Probable small intestine urate exporter protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-132817 / sc-132816
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunofluorescence (IF)

(Immunofluorescent analysis of Hela cells using MBS7004490 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of Hela cells using MBS7004490 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-SLC17A4 antibody
Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,243 Da
NCBI Official Full Name
probable small intestine urate exporter isoform b
NCBI Official Synonym Full Names
solute carrier family 17, member 4
NCBI Official Symbol
SLC17A4
NCBI Official Synonym Symbols
KAIA2138
NCBI Protein Information
probable small intestine urate exporter
UniProt Protein Name
Probable small intestine urate exporter
UniProt Gene Name
SLC17A4
UniProt Entry Name
S17A4_HUMAN

NCBI Description

Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]).[supplied by OMIM, Feb 2011]

Uniprot Description

SLC17A4: May be involved in actively transporting phosphate into cells via Na(+) cotransport. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 6p22.2

Cellular Component: apical plasma membrane; integral to plasma membrane; membrane

Molecular Function: sodium-dependent phosphate transmembrane transporter activity; sodium:phosphate symporter activity

Biological Process: phosphate metabolic process; sodium ion transport

Research Articles on SLC17A4

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Product Notes

The SLC17A4 slc17a4 (Catalog #AAA7004490) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC17A4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC17A4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF). Researchers should empirically determine the suitability of the SLC17A4 slc17a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC17A4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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