CD150 (SLAM) Recombinant Protein | CD150 recombinant protein
Human CD150 Recombinant (SLAM)
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Avoid repeated freeze/thaw cycles.
• measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (slam, CD150) .J. Virol., Dec 2009; 10.1128/JVI.01559-09.
• human and rhesus macaque hematopoietic stem cells are not enriched in the CD150+cd48- slam population. .Blood (ASH Annual Meeting Abstracts), Nov 2009; 114: 3531.
• dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (slam, CD150) .J. Biol. Chem., Apr 2008; 283: 11763 - 11771.
• CD150– side population cells represent a functionally distinct population of long-term hematopoietic stem cells .Blood, Feb 2008; 111: 2444 - 2451.
NCBI and Uniprot Product Information
Uniprot Description
SLAM: a type I membrane protein present on the surface of B cells, T cells and CD83+ dendritic cells. A high-affinity self-ligand considered to be important in bidirectional T <-> B-cell stimulation. SLAM-induced signal-transduction events in T lymphocytes are different from those in B cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A (SAP) acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (SHP-2)-dependent signal transduction operates. Its cytoplasmic domain interacts with SAP through part of its SH2 domain, and with SHP-2. Three alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: integral to membrane; phagocytic vesicle; external side of plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; antigen binding
Biological Process: viral reproduction; regulation of catalytic activity; regulation of vesicle fusion; positive regulation of cell proliferation; lymphocyte activation; signal transduction
Similar Products
Product Notes
The CD150 slamf1 (Catalog #AAA553183) is a Recombinant Protein produced from HEk293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD150 (SLAM), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
