Testing Data
Rabbit anti-Human, Rat SLAM/CD150 Polyclonal Antibody | anti-SLAM/CD150 antibody
SLAM / CD150 Antibody
Appearance: Colorless liquid
Shelf Life: 12 months
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
SLAM: a type I membrane protein present on the surface of B cells, T cells and CD83+ dendritic cells. A high-affinity self-ligand considered to be important in bidirectional T <-> B-cell stimulation. SLAM-induced signal-transduction events in T lymphocytes are different from those in B cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A (SAP) acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (SHP-2)-dependent signal transduction operates. Its cytoplasmic domain interacts with SAP through part of its SH2 domain, and with SHP-2. Three alternatively spliced isoforms have been described.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: integral to membrane; phagocytic vesicle; external side of plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; antigen binding
Biological Process: viral reproduction; regulation of catalytic activity; regulation of vesicle fusion; positive regulation of cell proliferation; lymphocyte activation; signal transduction
Research Articles on SLAM/CD150
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Product Notes
The SLAM/CD150 slamf1 (Catalog #AAA840639) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLAM / CD150 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLAM/CD150 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (3-6 mg/ml). However, the optimal concentrations should be determined individually. Researchers should empirically determine the suitability of the SLAM/CD150 slamf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLAM/CD150, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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