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SIRPB2 recombinant protein
Recombinant Human SIRPB2 (C-Fc)
Gene Names
SIRPB2; PTPN1L; PTPNS1L3; dJ776F14.2
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
SIRPB2; Recombinant Human SIRPB2 (C-Fc); dJ776F14.2; PTPN1L; PTPNS1L3; Signal-Regulatory Protein Beta 2; Signal-Regulatory Protein Beta-2; SIRP beta 2; SIRP-beta-2; SIRPG; SIRPB2 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2um filtered solution of PBS, pH7.4.
Sequence
Gln33-Gly287
Species
Human
Tag
C-Fc
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Human Signal-regulatory Protein Beta-2 is produced by our Mammalian expression system and the target gene encoding Gln33-Gly287 is expressed with a Fc tag at the C-terminus.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.
This product is provided as lyophilized powder which is shipped with ice packs.
SDS-Page
SDS-Page
Related Product Information for SIRPB2 recombinant protein
Signal-regulatory protein beta-2(SIRP-beta-2), is a monomeric single pass type I membrane glycoprotein, belongs to the SIRP/SHPS (CD172) family of the immunoglobulin (Ig) superfamily. The SIRP family are paired receptors that have similar extracellular domains but differing C-terminal domains and functions. A positively charged residue within the transmembrane domain, in analogy to SIRP-beta-1, is implicated to mediate interaction with the adaptor DAP12 protein, which contains immunoreceptor tyrosine-based activation motifs (ITAMs). Proteins in the SIRP family are typically expressed in immune cells, especially in the myeloid lineages. Based on expression patterns, SIRPs are thought to have roles in immune regulation. SIRP family members role in innate immunity and host defense has potential significance as a therapeutic target in cancer and inflammation. There are currently no known mouse or rat homologs for this protein.
Product Categories/Family for SIRPB2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,968 Da
NCBI Official Full Name
signal-regulatory protein beta-2 isoform 2
NCBI Official Synonym Full Names
signal-regulatory protein beta 2
NCBI Official Symbol
SIRPB2
NCBI Official Synonym Symbols
PTPN1L; PTPNS1L3; dJ776F14.2
NCBI Protein Information
signal-regulatory protein beta-2; SIRP-beta-2; protein tyrosine phosphatase non-receptor type substrate protein; protein tyrosine phosphatase non-receptor type substrate 1-like 3; protein tyrosine phosphatase, non-receptor type substrate 1-like 3
UniProt Protein Name
Signal-regulatory protein beta-2
Protein Family
UniProt Gene Name
SIRPB2
UniProt Synonym Gene Names
PTPN1L; PTPNS1L3; SIRP-beta-2
UniProt Entry Name
SIRB2_HUMAN
Uniprot Description
SIRPB2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: integral to membrane
Research Articles on SIRPB2
Similar Products
Product Notes
The SIRPB2 sirpb2 (Catalog #AAA2569109) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gln33-Gly2 87. It is sometimes possible for the material contained within the vial of "SIRPB2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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