NCBI Description
This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Uniprot Description
TST: Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity. Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.
Protein type: Transferase; EC 2.8.1.1; Mitochondrial
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: extracellular space; mitochondrion; mitochondrial matrix; mitochondrial inner membrane
Molecular Function: thiosulfate sulfurtransferase activity; 5S rRNA binding
Biological Process: cyanate catabolic process; epithelial cell differentiation; sulfur amino acid metabolic process; rRNA transport; sulfur amino acid catabolic process
Product Notes
The Sheep TST tst (Catalog #
AAA7234917) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7234917 ELISA Kit recognizes Sheep TST.
It is sometimes possible for the material contained within the vial of
"Thiosulfate sulfurtransferase (TST), ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
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product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
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responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
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of any product performance
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