SFTPA2B Blocking Peptide | SFTPA2 blocking peptide
SFTPA2B Antibody (C-term) Blocking peptide
NCBI and Uniprot Product Information
NCBI Description
This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009]
Uniprot Description
SFTPA2: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF). Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease. Belongs to the SFTPA family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q22.3
Cellular Component: clathrin-coated endocytic vesicle; endoplasmic reticulum membrane; extracellular region; lamellar body
Biological Process: cellular protein metabolic process
Disease: Pulmonary Fibrosis, Idiopathic
Research Articles on SFTPA2
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Product Notes
The SFTPA2 sftpa2 (Catalog #AAA9218952) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SFTPA2B, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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