Serpin I2 (SERPINI2) Recombinant Protein | SERPINI2 recombinant protein
Recombinant Human Serpin I2 (SERPINI2)
Gene Names
SERPINI2; MEPI; PI14; PANCPIN; TSA2004
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Serpin I2 (SERPINI2); Recombinant Human Serpin I2 (SERPINI2); SERPINI2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
19-405, Full length protein
Sequence
SRCSAQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL
Sequence Length
387
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for SERPINI2 recombinant protein
This protein is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,145 Da
NCBI Official Full Name
serpin I2 isoform 1
NCBI Official Synonym Full Names
serpin family I member 2
NCBI Official Symbol
SERPINI2
NCBI Official Synonym Symbols
MEPI; PI14; PANCPIN; TSA2004
NCBI Protein Information
serpin I2
UniProt Protein Name
Serpin I2
Protein Family
UniProt Gene Name
SERPINI2
UniProt Synonym Gene Names
MEPI; PI14; PI-14
NCBI Description
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Research Articles on SERPINI2
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Product Notes
The SERPINI2 serpini2 (Catalog #AAA1000160) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-405, Full length protein. The amino acid sequence is listed below: SRCSAQKNTE FAVDLYQEVS LSHKDNIIFS PLGITLVLEM VQLGAKGKAQ QQIRQTLKQQ ETSAGEEFFV LKSFFSAISE KKQEFTFNLA NALYLQEGFT VKEQYLHGNK EFFQSAIKLV DFQDAKACAE MISTWVERKT DGKIKDMFSG EEFGPLTRLV LVNAIYFKGD WKQKFRKEDT QLINFTKKNG STVKIPMMKA LLRTKYGYFS ESSLNYQVLE LSYKGDEFSL IIILPAEGMD IEEVEKLITA QQILKWLSEM QEEEVEISLP RFKVEQKVDF KDVLYSLNIT EIFSGGCDLS GITDSSEVYV SQVTQKVFFE INEDGSEAAT STGIHIPVIM SLAQSQFIAN HPFLFIMKHN PTESILFMGR VTNPDTQEIK GRDLDSL. It is sometimes possible for the material contained within the vial of "Serpin I2 (SERPINI2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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