Serpin B5/Maspin Recombinant Protein | SERPINB5 recombinant protein
Recombinant Serpin B5/Maspin
Gene Names
SERPINB5; PI5; maspin
Applications
SDS-Page
Purity
>90% by SDS-PAGE
Synonyms
Serpin B5/Maspin; Recombinant Serpin B5/Maspin; Acrosomal serine protease inhibitor; IPSP; IPSP_HUMAN; PAI 3; PAI-3; PAI3; PCI; PCI-B; PLANH 3; PLANH3; Plasma serine protease inhibitor; Plasminogen activator inhibitor 3; Plasminogen activator inhibitor III; PROCI; Protein C inhibitor; Serpin A5; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 5; Serpin peptidase inhibitor clade A member 5; Serpina5; SERPINB5 recombinant protein
Host
E Coli
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid; 20mM Tris-HCl Buffer (pH8.0) Containing 10% Glycerol, 1mM DTT.
Concentration
0.5mg/ml (determined by Bradford assay) (varies by lot)
Sequence Positions
1-375aa
Sequence
MGSSHHHHHH SSGLVPRGSH MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDVPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFSESET KECPFRVNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP
Sequence Length
375
Applicable Applications for SERPINB5 recombinant protein
SDS-PAGE
Species
Human
Endotoxin
<1 EU per 1ug of protein (determined by LAL method)
Tag
His-Tag
Preparation and Storage
Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for SERPINB5 recombinant protein
Serpin B5/Maspin, also known as serpin family B member 5, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but down regulated in the respective carcinomas. Recombinant human Serpin B5/Maspin, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for SERPINB5 recombinant protein
References
Lockett J., et al. (2006) J Cell Biochem. 97(4):651-60. Khalkhali Ellis Z., et al. (2006) Clin Cancer Res. 12(24):7279-83.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44.2 kDa (395 aa), confirmed by MALDI-TOF
NCBI Official Full Name
serpin B5
NCBI Official Synonym Full Names
serpin family B member 5
NCBI Official Symbol
SERPINB5
NCBI Official Synonym Symbols
PI5; maspin
NCBI Protein Information
serpin B5
UniProt Protein Name
Serpin B5
Protein Family
UniProt Gene Name
SERPINB5
UniProt Synonym Gene Names
PI5; PI-5
UniProt Entry Name
SPB5_HUMAN
