SDS-PAGE
Serpinb10 recombinant protein
Recombinant Mouse SerpinB10 Protein (His tag)
Gene Names
Serpinb10; BB233602; 9830131G07; Serpinb10-ps
Purity
> 94 % as determined by SDS-PAGE
Synonyms
SerpinB10; Recombinant Mouse SerpinB10 Protein (His tag); BB233602; Serpinb10; 9830131G07; Serpinb10-ps; Serpinb10 recombinant protein
Host
Baculovirus-Insect Cells
Purity/Purification
> 94 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0
Sequence Length
397
Application Notes
The recombinant mouse SERPINB10 consists of 408 amino acids and has a calculated molecular mass of 46.5 kDa. It migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Met
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for Serpinb10 recombinant protein
Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1000 serpins have been identified. Mouse SerpinB10, also known as Peptidase inhibitor 10, PI-10, Bomapin and SERPINB10, is a nucleus and cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. SerpinB10 is expressed specifically in the bone marrow. SerpinB10 is a protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. SerpinB10 is a redox-sensitive nuclear serpin that augments proliferation or apoptosis of leukaemia cells, depending on growth factors availability. SerpinB10 may regulate protease activities in the cytoplasm and in the nucleus.
Description: A DNA sequence encoding the mouse SERPINB10 (Q8K1K6-1) (Met 1-Pro 397) was expressed, with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the mouse SERPINB10 (Q8K1K6-1) (Met 1-Pro 397) was expressed, with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
45,115 Da
NCBI Official Full Name
Serpin B10
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
NCBI Official Symbol
Serpinb10
NCBI Official Synonym Symbols
BB233602; 9830131G07; Serpinb10-ps
NCBI Protein Information
serpin B10
UniProt Protein Name
Serpin B10
Protein Family
UniProt Gene Name
Serpinb10
Uniprot Description
SERPINB10: Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. Belongs to the serpin family. Ov-serpin subfamily.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 1|1 E2.1
Cellular Component: extracellular space
Molecular Function: protease inhibitor activity; serine-type endopeptidase inhibitor activity
Biological Process: negative regulation of proteolysis
Similar Products
Product Notes
The Serpinb10 serpinb10 (Catalog #AAA2546879) is a Recombinant Protein produced from Baculovirus-Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse SERPINB10 consists of 408 amino acids and has a calculated molecular mass of 46.5 kDa. It migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the Serpinb10 serpinb10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SerpinB10, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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