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Protein transport protein Sec61 subunit beta Recombinant Protein | SEC61B recombinant protein

Protein transport protein Sec61 subunit beta

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protein transport protein Sec61 subunit beta; SEC61B recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
2-96aa; full length protein
Sequence
PGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS
Sequence Length
Full Length Protein
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for SEC61B recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Product Categories/Family for SEC61B recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,974 Da
NCBI Official Full Name
protein transport protein Sec61 subunit beta
NCBI Official Synonym Full Names
Sec61 translocon beta subunit
NCBI Official Symbol
SEC61B
NCBI Protein Information
protein transport protein Sec61 subunit beta
UniProt Protein Name
Protein transport protein Sec61 subunit beta
Protein Family
UniProt Gene Name
SEC61B
UniProt Entry Name
SC61B_HUMAN

NCBI Description

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]

Uniprot Description

SEC61B: Necessary for protein translocation in the endoplasmic reticulum. Belongs to the SEC61-beta family.

Protein type: Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q22.33

Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; membrane

Molecular Function: epidermal growth factor binding; protein binding

Biological Process: ER-associated protein catabolic process; protein import into nucleus, translocation; retrograde protein transport, ER to cytosol

Research Articles on SEC61B

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Product Notes

The SEC61B sec61b (Catalog #AAA7043297) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-96aa; full length protein. The amino acid sequence is listed below: PGPTPSGTNV GSSGRSPSKA VAARAAGSTV RQRKNASCGT RSAGRTTSAG TGGMWRFYTE DSPGLKVGPV PVLVMSLLFI ASVFMLHIWG KYTRS. It is sometimes possible for the material contained within the vial of "Protein transport protein Sec61 subunit beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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