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135 results for "IL12 signaling pathway" - showing 1-50
Activity Data
(Suppressor of cytokine signaling 3 (SOCS3) is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family that negatively regulates cytokine signal transduction. SOCS3 is feedback inhibitors of the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signaling pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. SOCS3 also can bind to JAK2 kinase inhibits its kinase activity and nhibits insulin signaling in adipose tissue and the liver. Besides, Glycoprotein 130 (gp130) has been identified as an interactor of SOCS3, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse SOCS3 and recombinant mouse gp130. Briefly, SOCS3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to SOCS3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-SOCS3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of SOCS3 and gp130 was shown in Figure 1, and this effect was in a dose dependent manner.)
Suppressors Of Cytokine Signaling 3 (SOCS3), Active Protein (Cat# AAA2097298)
Full Name
Active Suppressors Of Cytokine Signaling 3 (SOCS3)
Gene Names
Socs3; Cis3; Ef10; Ssi3; Cish3; EF-10; SSI-3
Reactivity
Mouse
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$215/0.01 mg | $450/0.05 mg | $690/0.1 mg | $850/0.2 mg | $1,660/0.5 mg | $2,470/1 mg | $6,035/5 mg
Western Blot (WB)
(All lanes : Anti-IL12RB2 Antibody (C-term) at 1:2000 dilutionLane 1: THP-1 whole cell lysateLane 2: A431 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: MOLT-4 whole cell lysate Lysates/proteins at 20 ug per lane.Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 97 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
IL12_2, Polyclonal Antibody (Cat# AAA9212524)
Full Name
IL12_2 Antibody (C-term)
Reactivity
Human
Applications
WB, IHC-P, FC, EIA
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
CD40 Ligand (CD40LG), Active Protein (Cat# AAA7115116)
Full Name
Recombinant Human CD40 Ligand (CD40LG), Partial
Gene Names
CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$165/0.01 mg | $285/0.05 mg | $1,170/5x0.05 mg
SOCS3, Positive Control (Cat# AAA543274)
Full Name
SOCS3 Antibody Western Blot Positive Control
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Applications
WB
Pricing
$335/5 Applications | $1,350/5x5 Applications
SOCS3, Polyclonal Antibody (Cat# AAA544939)
Full Name
SOCS3 Antibody FITC-Conjugated
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
EIA, WB
Pricing
$560/0.1 mg | $2,380/5x0.1 mg
Western Blot (WB)
SOCS3, Polyclonal Antibody (Cat# AAA544937)
Full Name
SOCS3 Antibody Affinity Purified
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
EIA, WB
Pricing
$445/0.1 mg | $1,855/5x0.1 mg
SOCS3, Polyclonal Antibody (Cat# AAA544938)
Full Name
SOCS3 Antibody BIOTIN-Conjugated
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
EIA, WB
Pricing
$560/0.1 mg | $2,380/5x0.1 mg
SOCS3, Blocking Peptide (Cat# AAA544498)
Full Name
SOCS3 Antibody Antigenic Blocking Peptide
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Applications
Immunocompetition, Immunodepletion
Pricing
$280/0.25 mg | $1,110/5x0.25 mg
IL-12 p70/IL12A, Monoclonal Antibody (Cat# AAA8100161)
Full Name
Recombinant Anti-IL-12 p70/IL12A Antibody, Rabbit Monoclonal
Gene Names
IL12A; P35; CLMF; NFSK; NKSF1; IL-12A
Reactivity
Human
Applications
EIA
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
SDS-Page
Interferon Gamma, Active Protein (Cat# AAA8122933)
Full Name
Interferon Gamma Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Ifng; Ifg; IFN-g
Purity
>92% as determined by SDS-PAGE
Pricing
$340/0.1 mg | $1,380/5x0.1 mg
Interferon Gamma, Polyclonal Antibody (Cat# AAA8111955)
Full Name
Anti-Interferon Gamma Antibody, Rabbit Polyclonal
Gene Names
Ifng; Ifg; IFN-g
Reactivity
Mouse
Applications
EIA
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105722)
Full Name
Recombinant Anti-Interferon Gamma Antibody (HRP), Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$375/0.1 mg | $1,545/5x0.1 mg
IL-27, Monoclonal Antibody (Cat# AAA8100668)
Full Name
Recombinant Anti-IL-27 Antibody, Rabbit Monoclonal
Gene Names
EBI3; IL27B; IL-27B
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
IL-12 p70/IL12A, Monoclonal Antibody (Cat# AAA8100160)
Full Name
Anti-IL-12 p70/IL12A Antibody, Mouse Monoclonal
Gene Names
IL12A; P35; CLMF; NFSK; NKSF1; IL-12A
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL17, Cell Lysate (Cat# AAA8117208)
Full Name
Rabbit IL17 Baculovirus-Insect Overexpression Lysate
Applications
WB
Pricing
$280/0.3 mg | $1,205/5x0.3 mg
Immunohistochemistry (IHC)
(Immunochemical staining of mouse IFNG in mouse kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Interferon Gamma, Polyclonal Antibody (Cat# AAA8103309)
Full Name
Anti-Interferon Gamma Antibody, Rabbit Polyclonal
Gene Names
Ifng; Ifg; IFN-g
Reactivity
Mouse
Applications
IHC-P
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL17, Monoclonal Antibody (Cat# AAA8106125)
Full Name
Anti-IL17 Antibody, Mouse Monoclonal
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Reactivity
Human
Applications
EIA, Det
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $975/1 mL | $4,240/5x1 mL
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Mouse Interferon gamma expression on BABL/c splenocytes. BABL/c splenocytes were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer's manual, stained with PE-conjugated anti-Mouse Interferon gamma and APC-conjugated anti-Mouse CD4. The dot plots were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Interferon Gamma, Monoclonal Antibody (Cat# AAA8119584)
Full Name
Recombinant Anti-Interferon Gamma Antibody (PE), Rabbit Monoclonal
Reactivity
Mouse
Applications
FC/FACS
Purity
Protein A
Pricing
$150/100 Tests | $130/25 Tests | $525/5x100 Tests
IL-12, Monoclonal Antibody (Cat# AAA8113321)
Full Name
Recombinant Anti-IL-12 Antibody, Rabbit Monoclonal
Gene Names
IL12B; CLMF; NKSF; CLMF2; NKSF2; IL-12B
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Mouse Interferon gamma expression on BABL/c splenocytes. BABL/c splenocytes were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer's manual, stained with purified anti-Mouse Interferon gamma, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Interferon Gamma, Monoclonal Antibody (Cat# AAA8119585)
Full Name
Recombinant Anti-Interferon Gamma Antibody, Rabbit Monoclonal
Reactivity
Mouse
Applications
FC/FACS
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human IFN-gamma expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer's manual (BD Pharmingen'), stained with PE-conjugated anti-Human IFN-gamma and FITC-conjugated anti-Human CD3. The dot plots were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.)
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105717)
Full Name
Recombinant Anti-Interferon Gamma Antibody (PE), Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
FC/FACS/FCM
Purity
Protein A
Pricing
$275/100 Tests | $185/25 Tests | $1,080/5x100 Tests
Interferon Gamma, Polyclonal Antibody (Cat# AAA8113123)
Full Name
Anti-Interferon Gamma Antibody, Rabbit Polyclonal
Gene Names
IFNG; IFN-gamma
Reactivity
Rhesus
Applications
EIA
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL-27, Polyclonal Antibody (Cat# AAA8100669)
Full Name
Anti-IL-27 Antibody, Rabbit Polyclonal
Gene Names
EBI3; IL27B; IL-27B
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$190/0.1 mL | $240/0.2 mL | $280/0.4 mL | $1,110/5x0.4 mL
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105719)
Full Name
Recombinant Anti-Interferon Gamma Antibody (HRP), Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$375/0.1 mg | $1,545/5x0.1 mg
IL17, Monoclonal Antibody (Cat# AAA8106123)
Full Name
Anti-IL17 Antibody, Mouse Monoclonal
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
Testing Data
Interferon Gamma, Recombinant Protein (Cat# AAA8118672)
Full Name
Interferon Gamma Protein, Human, Recombinant
Gene Names
IFNG; IFG; IFI
Purity
>92 % as determined by SDS-PAGE
Pricing
$160/0.02 mg | $225/0.1 mg | $970/1 mg | $4,225/5x1 mg
Testing Data
Interferon Gamma, ELISA Pair Set (Cat# AAA8118572)
Full Name
Interferon Gamma Matched ELISA Antibody Pair Set, Human
Pricing
$300/5 Plates | $560/15 Plates | $2,565/5x15 Plates
SDS-Page
Interferon Gamma, Active Protein (Cat# AAA8122934)
Full Name
Interferon Gamma Protein, Mouse, Recombinant (His Tag)
Gene Names
Ifng; Ifg; IFN-g
Purity
>75% as determined by SDS-PAGE
Pricing
$340/0.1 mg | $1,380/5x0.1 mg
IL-12, Cell Lysate (Cat# AAA8118096)
Full Name
Rhesus IL-12 HEK293 Overexpression Lysate
Gene Names
IL12A; IL-12A
Applications
WB
Pricing
$280/0.3 mg | $1,205/5x0.3 mg
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105723)
Full Name
Recombinant Anti-Interferon Gamma Antibody, Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
EIA, Cap
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,275/1 mL | $5,580/5x1 mL
IL12B, Polyclonal Antibody (Cat# AAA8112968)
Full Name
Anti-IL12B Antibody, Rabbit Polyclonal
Gene Names
Il12b; Il12
Reactivity
Rat
Applications
EIA
Purity
Protein A
Pricing
$190/0.1 mL | $240/0.2 mL | $280/0.4 mL | $1,110/5x0.4 mL
IL12B, Polyclonal Antibody (Cat# AAA8100469)
Full Name
Anti-IL12B Antibody, Rabbit Polyclonal
Gene Names
IL12B; CLMF; NKSF; CLMF2; NKSF2; IL-12B
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$190/0.1 mL | $240/0.2 mL | $280/0.4 mL | $1,110/5x0.4 mL
IL-12, Polyclonal Antibody (Cat# AAA8113339)
Full Name
Anti-IL-12 Antibody, Rabbit Polyclonal
Reactivity
Mouse
Applications
EIA
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL12B, Monoclonal Antibody (Cat# AAA8100466)
Full Name
Anti-IL12B Antibody, Mouse Monoclonal
Gene Names
IL12B; CLMF; NKSF; CLMF2; NKSF2; IL-12B
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL-12, Monoclonal Antibody (Cat# AAA8113322)
Full Name
Recombinant Anti-IL-12 Antibody, Rabbit Monoclonal
Gene Names
IL12B; CLMF; NKSF; CLMF2; NKSF2; IL-12B
Reactivity
Human
Applications
EIA, Det
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,275/1 mL | $5,580/5x1 mL
IL17, Monoclonal Antibody (Cat# AAA8106127)
Full Name
Anti-IL17 Antibody, Mouse Monoclonal
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human IFN-gamma expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer's manual (BD Pharmingen'), stained with purified anti-Human IFN-gamma, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.)
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105713)
Full Name
Recombinant Anti-Interferon Gamma Antibody, Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
FC/FACS/FCM
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
IL12B, Monoclonal Antibody (Cat# AAA8100465)
Full Name
Anti-IL12B Antibody, Mouse Monoclonal
Gene Names
IL12B; CLMF; NKSF; CLMF2; NKSF2; IL-12B
Reactivity
Human
Applications
EIA, Cap
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $975/1 mL | $4,240/5x1 mL
Testing Data
IL17, ELISA Pair Set (Cat# AAA8118419)
Full Name
IL17 Matched ELISA Antibody Pair Set, Human
Pricing
$300/5 Plates | $560/15 Plates | $2,565/5x15 Plates
Testing Data
IL12B, ELISA Pair Set (Cat# AAA8118575)
Full Name
IL12B Matched ELISA Antibody Pair Set, Human
Pricing
$300/5 Plates | $560/15 Plates | $2,565/5x15 Plates
Testing Data
(The ability of Human IL-17a Neutralizing Mouse mAb to inhibit IL-17A-induced IL-6 production was analyzed. IL6 secretion in the HFF human foreskin fibroblast induced by 50 ng/mL of Recombinant Human IL17a (12047-HNAE) is neutralized by increasing concentrations of mouse anti-Human IL17a neutralizing Monoclonal Antibody, as measured by IL6 Quantitative ELISA Kit.The IC50 is typically 0.23-0.94 ug/mL.)
IL17/IL17a, Monoclonal Antibody (Cat# AAA8106122)
Full Name
IL17/IL17a Neutralizing Antibody
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Reactivity
Human
Applications
BL
Purity
Protein A
Pricing
$280/0.2 mg | $375/0.5 mg | $1,545/5x0.5 mg
IL12B, Polyclonal Antibody (Cat# AAA8112250)
Full Name
Anti-IL12B Antibody, Rabbit Polyclonal
Reactivity
Mouse
Applications
EIA
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
Interferon Gamma, Monoclonal Antibody (Cat# AAA8111954)
Full Name
Recombinant Anti-Interferon Gamma Antibody, Rabbit Monoclonal
Gene Names
Ifng; Ifg; IFN-g
Reactivity
Mouse
Applications
EIA
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
Interferon Gamma, Polyclonal Antibody (Cat# AAA8113122)
Full Name
Anti-Interferon Gamma Antibody, Rabbit Polyclonal
Gene Names
IFNG; IFN-gamma
Reactivity
Rhesus
Applications
EIA
Purity
Protein A
Pricing
$190/0.1 mL | $240/0.2 mL | $280/0.4 mL | $1,110/5x0.4 mL
Interferon Gamma, Polyclonal Antibody (Cat# AAA8105726)
Full Name
Anti-Interferon Gamma Antibody, Rabbit Polyclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
EIA
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL17, Polyclonal Antibody (Cat# AAA8106128)
Full Name
Anti-IL17 Antibody, Rabbit Polyclonal
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Reactivity
Human
Applications
EIA
Purity
Protein A & Antigen Affinity
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105724)
Full Name
Recombinant Anti-Interferon Gamma Antibody, Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,110/5x0.1 mL
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105712)
Full Name
Anti-Interferon Gamma Antibody, Mouse Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
WB
Purity
Protein A
Pricing
$190/0.05 mL | $240/0.1 mL | $280/0.2 mL | $1,110/5x0.2 mL
IL17, Monoclonal Antibody (Cat# AAA8119039)
Full Name
Anti-IL17 Antibody (Biotin), Mouse Monoclonal
Reactivity
Human
Applications
EIA
Purity
Protein A
Pricing
$300/0.1 mg | $1,205/5x0.1 mg
Interferon Gamma, Monoclonal Antibody (Cat# AAA8105720)
Full Name
Recombinant Anti-Interferon Gamma Antibody, Rabbit Monoclonal
Gene Names
IFNG; IFG; IFI
Reactivity
Human
Applications
EIA, Det
Purity
Protein A
Pricing
$210/0.05 mL | $280/0.1 mL | $1,275/1 mL | $5,580/5x1 mL
