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47 results for "CDK7 inhibitor" - showing 1-47


Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, using HINT1 antibody.)

HINT1, Polyclonal Antibody (Cat# AAA9604653)

Full Name
HINT1 Antibody
Gene Names
HINT1; HINT; NMAN; PKCI-1; PRKCNH1
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunofluorescent (IF) (Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized U-2 OS (human bone osteosarcoma cell line) cells labeling HINT1 with MBS9200257 at 1/25 dilution, followed by Dylight® 488-conjugated goat anti-mouse IgG (NA166821) secondary antibody at 1/200 dilution (green). Immunofluorescence image showing cytoplasm staining on U-2 OS cell line. Cytoplasmic actin is detected with Dylight® 554 Phalloidin (PD18466410) at 1/100 dilution (red).The nuclear counter stain is DAPI (blue))

HINT1, Monoclonal Antibody (Cat# AAA9200257)

Full Name
HINT1 Antibody
Gene Names
HINT1; HINT; NMAN; PKCI-1; PRKCNH1
Reactivity
Human, mouse, rat
Applications
F, IHC-P, FC, WB,E
Purity
Purified Mouse Monoclonal Antibody (Mab)
Pricing
$425/0.4 mL | $190/0.08 mL | $1,665/5x0.4 mL
Immunoflurescence (IF)/Immunocytochemistry (ICC) (Staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. Samples were then incubated with primary Ab(BF8013) and rabbit anti-beta tubulin Ab(AF7011) for 1 hour at 37 degree C. An AlexaFluor594 conjugated goat anti-mouse IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-rabbit IgG(H+L) Ab(Green) were used as the secondary antibody.The nuclear counter stain is DAPI (blue).)

p53, Monoclonal Antibody (Cat# AAA9629032)

Full Name
p53 Mouse monoclonal Antibody
Gene Names
TP53; P53; BCC7; LFS1; TRP53
Reactivity
Human, Mouse
Applications
WB, IF, ICC
Purity
Affinity-chromatography.
Pricing
$280/0.1 mL | $325/0.2 mL | $1,305/5x0.2 mL
Testing Data (PHA-793887 is a novel pan-cdk inhibitor, including cdk1, cdk2, cdk4, cdk5, cdk7, and cdk9 with IC50 in the 5 to 140 nM range. [1]It is inactive against other 34 kinases representative of all kinase families, in particular c-abl, c-kit, lck, and TRKA with IC50>10 mM. It shows anti-proliferative activity against several solid tumor cell lines, with IC50, 1 mM. In these cells, it is able to inhibit Rb phosphorylation and expression of S-phase cyclins, such as cyclin A. [1,2])

PHA-793887, Inhibitor (Cat# AAA8506269)

Full Name
PHA-793887
Pricing
$715/5 mg | $3,165/5x5 mg

THZ1, Inhibitor (Cat# AAA578530)

Full Name
THZ1
Purity
99.3%
Pricing
$230/5 mg | $275/10 mg | $360/25 mg | $480/50 mg | $715/100 mg | $2,945/5x100 mg

Flavopiridol, Inhibitor (Cat# AAA579364)

Full Name
Flavopiridol (Alvocidib)
Purity
98.0%
Pricing
$200/5 mg | $210/10 mg | $255/25 mg | $340/50 mg | $500/100 mg | $805/200 mg | $200/1mL*10mM (in DMSO) | $3,315/5x200 mg

KRP4, Polyclonal Antibody (Cat# AAA9003002)

Full Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KRP4 Polyclonal Antibody
Gene Names
AT2G32710; ACK2; CYCLIN-DEPENDENT KINASE INHIBITOR 2; F24L7.15; F24L7_15; ICK7; INTERACTORS OF CDC2 KINASE 7; KIP-RELATED PROTEIN 4
Reactivity
Arabidopsis thaliana (Mouse-ear cress)
Applications
EIA, Western Blot, ensure identification of antigen
Purity
Protein A/G
Structure

LDC4297, Inhibitor (Cat# AAA3607301)

Full Name
LDC4297
Purity
>98% (HPLC)
Pricing
$240/5 mg | $295/10 mg | $430/25 mg | $665/50 mg | $2,715/5x50 mg

TP53 / Cellular Tumor Antigen P53, Recombinant Protein (Cat# AAA2901976)

Full Name
Human TP53 / Cellular Tumor Antigen P53 Recombinant Protein
Gene Names
TP53; P53; BCC7; LFS1; BMFS5; TRP53
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Structure

Lerociclib dihydrochloride, Inhibitor (Cat# AAA5753154)

Full Name
Lerociclib dihydrochloride
Purity
98.00%
Pricing
$365/1 mg | $620/5 mg | $890/10 mg | $1,695/25 mg | $2,595/50 mg | $3,650/100 mg | $16,145/5x100 mg
Chemical Structure

THZ1-Hydrochloride, CDK7 inhibitor, Inhibitor (Cat# AAA130268)

Full Name
THZ1-Hydrochloride, CDK7 inhibitor
Purity
98%
Pricing
$1,055/100 mg | $2,765/500 mg

LY2857785, Inhibitor (Cat# AAA5764318)

Full Name
LY2857785
Purity
98.00%
Pricing
$455/10 mg | $805/25 mg | $1,220/50 mg | $2,090/100 mg | $9,115/5x100 mg
Structure

THZ1-R, Inhibitor (Cat# AAA5754043)

Full Name
THZ1-R
Purity
98.00%
Pricing
$275/1 mg | $425/5 mg | $600/10 mg | $1,525/50 mg | $2,080/100 mg | $9,065/5x100 mg
Structure

LDC-4297 HCl (1453834-21-3 (free base)), Inhibitor (Cat# AAA3607700)

Full Name
LDC-4297 HCl (1453834-21-3 (free base))
Purity
>98% (HPLC)
Pricing
$230/5 mg | $280/10 mg | $405/25 mg | $645/50 mg | $2,610/5x50 mg
Chemical Structure

LDC-4297 HCl, Inhibitor (Cat# AAA5750536)

Full Name
LDC-4297 HCl (1453834-21-3(Free Base))
Purity
99.8%
Pricing
$205/1 mg | $225/2 mg | $240/5 mg | $305/10 mg | $475/25 mg | $760/50 mg | $240/1 mL (in DMSO) | $3,155/5x50 mg
Structure

(R)?-?CR8 trihydrochloride, Inhibitor (Cat# AAA5753767)

Full Name
(R)?-?CR8 trihydrochloride
Purity
98.00%
Pricing
$275/5 mg | $345/10 mg | $1,060/50 mg | $1,735/100 mg | $300/1mL*10mM (in DMSO) | $7,535/5x100 mg
Structure

BS-181, Inhibitor (Cat# AAA3600348)

Full Name
BS-181
Purity
>98% (HPLC)
Pricing
$205/2 mg | $230/5 mg | $265/10 mg | $455/50 mg | $1,760/5x50 mg
Structure

BS-181 hydrochloride, Inhibitor (Cat# AAA3601657)

Full Name
BS-181 hydrochloride
Purity
>98% (HPLC)
Pricing
$215/2 mg | $230/5 mg | $265/10 mg | $355/25 mg | $455/50 mg | $1,760/5x50 mg
Chemical Structure

THZ1, CDK7 inhibitor, Inhibitor (Cat# AAA130269)

Full Name
THZ1, CDK7 inhibitor
Purity
98%
Pricing
$1,055/100 mg | $2,765/500 mg

BS-181 hydrochloride, Inhibitor (Cat# AAA3846411)

Full Name
BS-181 hydrochloride
Purity
>98%
Pricing
$420/1 mg | $1,155/5 mg | $1,900/10 mg | $8,485/5x10 mg
Structure

Longdaysin, Inhibitor (Cat# AAA5751780)

Full Name
Longdaysin
Purity
99.74%
Pricing
$200/1 mg | $240/5 mg | $295/10 mg | $470/25 mg | $730/50 mg | $940/100 mg | $245/1 mL (in DMSO) | $3,970/5x100 mg
Structure

Flavopiridol, Inhibitor (Cat# AAA3601992)

Full Name
Flavopiridol
Purity
>98% (HPLC)
Pricing
$190/5 mg | $205/10 mg | $245/25 mg | $320/50 mg | $465/100 mg | $730/200 mg | $3,000/5x200 mg
Structure

YKL-5-124 TFA, Inhibitor (Cat# AAA5754140)

Full Name
YKL-5-124 TFA
Purity
98.00%
Pricing
$355/5 mg | $500/10 mg | $430/1mL*10mM (in DMSO) | $1,965/5x10 mg
Structure

Samuraciclib hydrochloride, Inhibitor (Cat# AAA5752956)

Full Name
Samuraciclib hydrochloride
Purity
98.00%
Pricing
$255/1 mg | $365/5 mg | $480/10 mg | $760/25 mg | $370/1 mL (in DMSO) | $3,160/5x25 mg
Chemical Structure

CDK7-IN-1, Inhibitor (Cat# AAA130214)

Full Name
CDK7-IN-1
Purity
98%
Pricing
$1,055/100 mg | $2,765/500 mg

PF-562271 HCl, Inhibitor (Cat# AAA3609410)

Full Name
PF-562271 HCl
Purity
>98% (HPLC)
Structure

Longdaysin, Inhibitor (Cat# AAA3610101)

Full Name
Longdaysin
Purity
>98% (HPLC)
Pricing
$235/5 mg | $285/10 mg | $435/25 mg | $670/50 mg | $860/100 mg | $3,580/5x100 mg
Structure

NU6140, Inhibitor (Cat# AAA5755288)

Full Name
NU6140
Purity
98.00%
Pricing
$240/1 mg | $330/5 mg | $480/10 mg | $710/25 mg | $1,125/50 mg | $1,705/100 mg | $335/1 mL (in DMSO) | $7,400/5x100 mg
Structure

(R)-CR8, Inhibitor (Cat# AAA5753768)

Full Name
(R)-CR8
Purity
98.41%
Pricing
$560/5 mg | $905/10 mg | $3,795/5x10 mg
Structure

SY-1365, Inhibitor (Cat# AAA5753984)

Full Name
SY-1365
Purity
98.00%
Pricing
$425/5 mg | $680/10 mg | $1,820/50 mg | $3,075/100 mg | $515/1 mL (in DMSO) | $13,570/5x100 mg
Structure

THZ-1 hydrochloride, Inhibitor (Cat# AAA3606935)

Full Name
THZ-1 hydrochloride
Purity
>98% (HPLC)
Pricing
$235/10 mg | $765/5x10 mg

bio-THZ1, Inhibitor (Cat# AAA3843023)

Full Name
bio-THZ1
Purity
>98%
Pricing
$455/5 mg | $805/10 mg | $2,360/50 mg | $10,570/5x50 mg
Structure

CDK7 and 9 inhibitor 14, Inhibitor (Cat# AAA3606183)

Full Name
CDK7 and 9 inhibitor 14
Purity
>98% (HPLC)
Structure

THZ2, Inhibitor (Cat# AAA5752444)

Full Name
THZ2
Purity
98.00%
Pricing
$265/2 mg | $310/5 mg | $365/10 mg | $545/25 mg | $795/50 mg | $1,220/100 mg | $350/1 mL (in DMSO) | $5,215/5x100 mg
Structure

PHA-793887, Inhibitor (Cat# AAA3605746)

Full Name
PHA-793887
Purity
>98% (HPLC)
Pricing
$210/2 mg | $240/5 mg | $280/10 mg | $420/25 mg | $610/50 mg | $900/100 mg | $3,750/5x100 mg
Structure

THZ-1, Inhibitor (Cat# AAA3602303)

Full Name
THZ-1
Purity
>98% (HPLC)
Pricing
$190/2 mg | $210/5 mg | $250/10 mg | $355/25 mg | $470/50 mg | $1,835/5x50 mg
Structure

Flavopiridol hydrochloride, Inhibitor (Cat# AAA3601289)

Full Name
Flavopiridol hydrochloride
Purity
>98% (HPLC)
Pricing
$200/5 mg | $215/10 mg | $280/25 mg | $315/50 mg | $480/100 mg | $1,870/5x100 mg

THZ1 Hydrochloride, Inhibitor (Cat# AAA5757918)

Full Name
THZ1 Hydrochloride
Purity
98.00%
Pricing
$225/5 mg | $280/10 mg | $395/25 mg | $240/1mL*10mM (in DMSO) | $1,495/5x25 mg
Structure

Roniciclib, Inhibitor (Cat# AAA5755477)

Full Name
Roniciclib
Purity
98.00%
Pricing
$425/5 mg | $595/10 mg | $1,820/50 mg | $3,075/100 mg | $455/1 mL (in DMSO) | $13,570/5x100 mg

LDC4297, Inhibitor (Cat# AAA3846040)

Full Name
LDC4297
Purity
>98%
Pricing
$155/2 mg | $225/5 mg | $375/10 mg | $1,000/50 mg | $4,465/5x50 mg
Chemical Structure

ICEC0942 HCl, Inhibitor (Cat# AAA3841880)

Full Name
ICEC0942 HCl
Purity
>98%
Pricing
$420/5 mg | $650/10 mg | $1,900/50 mg | $2,920/100 mg

THZ2, Inhibitor (Cat# AAA3846448)

Full Name
THZ2
Purity
>98%
Pricing
$285/5 mg | $445/10 mg | $1,215/50 mg | $2,390/100 mg

SY-1365, Inhibitor (Cat# AAA3842946)

Full Name
SY-1365
Purity
>98%
Pricing
$455/5 mg | $805/10 mg | $2,360/50 mg | $10,570/5x50 mg
Structure

SNS-032, Inhibitor (Cat# AAA3604182)

Full Name
SNS-032
Purity
>98% (HPLC)
Pricing
$190/5 mg | $205/10 mg | $225/25 mg | $260/50 mg | $330/100 mg | $1,195/5x100 mg
Structure

JSH-150, Inhibitor (Cat# AAA5759277)

Full Name
JSH-150
Purity
98.00%
Pricing
$345/2 mg | $560/5 mg | $900/1 mL (in DMSO) | $3,785/5x1 mL (in DMSO)
Structure

PHA-848125, Inhibitor (Cat# AAA3606002)

Full Name
PHA-848125
Purity
>98% (HPLC)
Pricing
$435/10 mg | $930/50 mg | $3,900/5x50 mg
Structure

CDKI-73, Inhibitor (Cat# AAA5754692)

Full Name
CDKI-73
Purity
98.00%
Pricing
$280/1 mg | $425/5 mg | $555/10 mg | $895/25 mg | $1,395/50 mg | $1,905/100 mg | $385/1 mL (in DMSO) | $8,310/5x100 mg
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