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42 results for "Aurora B inhibitor" - showing 1-42
Chemical Structure
(Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 ?M, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.)
Reversine, Inhibitor (Cat# AAA385676)
Full Name
Reversine
Purity
>98%
Pricing
$140/5 mg | $170/10 mg | $260/25 mg | $340/50 mg | $155/1 mL (in DMSO) | $1,465/5x50 mg
Structure
Danusertib, Inhibitor (Cat# AAA575889)
Full Name
Danusertib
Purity
98.4%
Pricing
$215/2 mg | $245/5 mg | $325/10 mg | $485/25 mg | $700/50 mg | $250/1 mL (in DMSO) | $2,875/5x50 mg
Molecular Structure
AICAR, Inhibitor (Cat# AAA515046)
Full Name
AICAR
Purity
>98% (TLC); NMR (Conforms)
Pricing
$190/50 mg | $285/250 mg | $1,050/5x250 mg
Immunohistochemistry (IHC)
(MO22161 antibody produces strong staining associated with chromosomes in prophase (A), the centromere in prometaphase and metaphase (B), the central mitotic spindle in anaphase (C), and midbodies between the two daughter cells during telophase and beyond (D). The vimentin antibody stains the intermediate filament network in these cells.)
Aurora B, Polyclonal Antibody (Cat# AAA555935)
Full Name
Aurora B Kinase
Gene Names
AURKB; AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; ARK-2; STK-1; STK12; PPP1R48; aurkb-sv1; aurkb-sv2
Reactivity
Human, Mouse, Rat
Applications
ICC, WB, IHC, IF
Purity
Affinity Purified
Pricing
$435/0.1 mL | $1,815/5x0.1 mL
Structure
MLN8054, Inhibitor (Cat# AAA578869)
Full Name
MLN8054
Purity
98.3%
Pricing
$215/2 mg | $240/5 mg | $310/10 mg | $445/25 mg | $740/50 mg | $1,030/100 mg | $240/1 mL (in DMSO) | $4,375/5x100 mg
Structure
CYC116, Inhibitor (Cat# AAA579001)
Full Name
CYC116
Purity
98.0%
Pricing
$215/10 mg | $290/25 mg | $365/50 mg | $560/100 mg | $910/200 mg | $210/1 mL (in DMSO) | $3,815/5x200 mg
Structure
AMG-900, Inhibitor (Cat# AAA578928)
Full Name
AMG-900
Purity
98.0%
Pricing
$210/2 mg | $255/5 mg | $325/10 mg | $510/25 mg | $730/50 mg | $265/1 mL (in DMSO) | $3,025/5x50 mg
Testing Data
(PHA-680632 is the first representative of a new class of Aurora inhibitors (Aurora A/B/C IC50 at 27, 135 and 120 nM, respectively). This agent has a high potential for further development as an anticancer therapeutic. PHA-680632 is active on a wide range of cancer cell lines and shows significant tumor growth inhibition in different animal tumor models at well-tolerated doses. The IC50 of PHA-680632 for cell anti-proliferation ranged from 0.11 uM to 5.6 uM. [1])
Immunohistochemistry (IHC)
(HeLa cell cultures were stained with MBS555934 antibody (green). The antibody stains spindle poles and mitotic spindles at anaphase (top 2 panels) and concentrates on the midbody between the two daughter cells during telophase (bottom 2 panels). It is therefore a useful marker of dividing cells. Cells were counterstained with our chicken polyclonal antibody to vimentin in red. Blue is a DNA stain.)
Aurora A/B, Monoclonal Antibody (Cat# AAA555934)
Full Name
Aurora A/B Kinase
Gene Names
AURKA; AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; PPP1R47
Reactivity
Rat, Cow, Pig, Horse, Human, Mouse
Applications
ICC, WB, IHC, IF
Purity
Affinity Purified
Pricing
$435/0.1 mL | $1,815/5x0.1 mL
Structure
Hesperadin, Inhibitor (Cat# AAA579073)
Full Name
Hesperadin
Purity
99.4%
Pricing
$185/2 mg | $205/5 mg | $225/10 mg | $265/25 mg | $330/50 mg | $480/100 mg | $205/1 mL (in DMSO) | $1,900/5x100 mg
Chemical Structure
(Chemical structure of ZM447439 (SIH-489), a Aurora B kinase inhibitor. CAS #: 331771-20-1. Molecular Formula: C29H31N5O4. Molecular Weight: 513.6 g/mol.)
ZM447439, Small Molecule (Cat# AAA808188)
Full Name
ZM447439
Purity
>=98% (TLC)
Pricing
$190/1 mg | $340/10 mg | $640/5x1 mg | $1,300/5x10 mg
SDS-Page
(Recombinant NSUN2 protein 10% SDS-PAGE Coomassie staining MW: 88.1 kDa Purity: >80%)
NSUN2, Recombinant Protein (Cat# AAA389226)
Full Name
Recombinant NSUN2 protein
Gene Names
NSUN2; MISU; MRT5; SAKI; TRM4
Pricing
$550/0.02 mg | $4,280/1 mg | $19,215/5x1 mg
Structure
Cenisertib, Inhibitor (Cat# AAA5754696)
Full Name
Cenisertib
Purity
98.00%
Pricing
$425/5 mg | $600/10 mg | $1,525/50 mg | $2,035/100 mg | $455/1mL*10mM (in DMSO) | $8,870/5x100 mg
Structure
GSK-1070916, Inhibitor (Cat# AAA3606743)
Full Name
GSK-1070916
Purity
>98% (HPLC)
Pricing
$230/5 mg | $280/10 mg | $500/50 mg | $1,975/5x50 mg
Structure
SCH-1473759, Inhibitor (Cat# AAA5755516)
Full Name
SCH-1473759
Purity
98.00%
Pricing
$300/2 mg | $370/5 mg | $470/10 mg | $975/50 mg | $1,355/100 mg | $5,815/5x100 mg
Structure
CCT 137690, Inhibitor (Cat# AAA3600372)
Full Name
CCT 137690
Purity
>98% (HPLC)
Pricing
$190/2 mg | $215/5 mg | $245/10 mg | $340/25 mg | $510/50 mg | $710/100 mg | $2,910/5x100 mg
Structure
Centrinone-B, Inhibitor (Cat# AAA5754697)
Full Name
Centrinone-B
Purity
98.00%
Pricing
$235/2 mg | $265/5 mg | $340/10 mg | $970/50 mg | $310/1mL*10mM (in DMSO) | $4,080/5x50 mg
Structure
SCH-1473759 hydrochloride, Inhibitor (Cat# AAA5753885)
Full Name
SCH-1473759 hydrochloride
Purity
98.00%
Pricing
$300/2 mg | $370/5 mg | $470/10 mg | $975/50 mg | $1,355/100 mg | $370/1mL*10mM (in DMSO) | $5,815/5x100 mg
Structure
MK8745, Inhibitor (Cat# AAA3609224)
Full Name
MK8745
Purity
>98% (HPLC)
Pricing
$190/5 mg | $210/10 mg | $245/25 mg | $305/50 mg | $395/100 mg | $610/200 mg | $2,465/5x200 mg
Structure
PHA-680632, Inhibitor (Cat# AAA3604368)
Full Name
PHA-680632
Purity
>98% (HPLC)
Pricing
$315/10 mg | $915/50 mg | $3,820/5x50 mg
Structure
TAK-901, Inhibitor (Cat# AAA3606675)
Full Name
TAK-901
Purity
>98% (HPLC)
Pricing
$205/2 mg | $245/5 mg | $310/10 mg | $495/25 mg | $695/50 mg | $2,855/5x50 mg
Structure
TAK632, Inhibitor (Cat# AAA3600890)
Full Name
TAK632
Purity
>98% (HPLC)
Pricing
$190/2 mg | $210/5 mg | $235/10 mg | $335/25 mg | $380/50 mg | $550/100 mg | $875/200 mg | $3,650/5x200 mg
SDS-Page
(Recombinant AURKB protein gel 10% SDS-PAGE with Coomassie staining MW: 40.5 kDa Purity: >80%)
AURKB, Recombinant Protein (Cat# AAA389396)
Full Name
Recombinant AURKB protein
Pricing
$565/0.02 mg | $4,215/1 mg | $18,905/5x1 mg
Structure
PF-03814735, Inhibitor (Cat# AAA3607673)
Full Name
PF-03814735
Purity
>98% (HPLC)
Pricing
$690/50 mg | $2,825/5x50 mg
Structure
NU6140, Inhibitor (Cat# AAA5755288)
Full Name
NU6140
Purity
98.00%
Pricing
$240/1 mg | $330/5 mg | $480/10 mg | $710/25 mg | $1,125/50 mg | $1,705/100 mg | $335/1 mL (in DMSO) | $7,400/5x100 mg
Structure
TAK-285, Inhibitor (Cat# AAA3607627)
Full Name
TAK-285
Purity
>98% (HPLC)
Pricing
$565/25 mg | $2,250/5x25 mg
Structure
G-749, Inhibitor (Cat# AAA3607304)
Full Name
G-749
Purity
>98% (HPLC)
Pricing
$230/2 mg | $250/5 mg | $330/10 mg | $560/25 mg | $865/50 mg | $3,600/5x50 mg
Structure
Aurora A-IN-10, Inhibitor (Cat# AAA3600550)
Full Name
Aurora A-IN-10
Purity
>98% (HPLC)
Pricing
$250/10 mg | $490/50 mg | $1,935/5x50 mg
Structure
Structure
Centrinone, Inhibitor (Cat# AAA5754698)
Full Name
Centrinone
Purity
98.00%
Pricing
$230/2 mg | $270/5 mg | $330/10 mg | $590/25 mg | $970/50 mg | $1,650/100 mg | $2,415/200 mg | $340/1 mL (in DMSO) | $10,605/5x200 mg
Structure
CCT241736, Inhibitor (Cat# AAA3607271)
Full Name
CCT241736
Purity
>98% (HPLC)
Pricing
$205/5 mg | $235/10 mg | $310/25 mg | $460/50 mg | $650/100 mg | $2,645/5x100 mg
Structure
AZD1152, Inhibitor (Cat# AAA5754559)
Full Name
AZD1152
Purity
98.00%
Pricing
$250/5 mg | $315/10 mg | $825/50 mg | $280/1mL*10mM (in DMSO) | $3,420/5x50 mg
SCH-1473759, Inhibitor (Cat# AAA3840173)
Full Name
SCH-1473759
Purity
>98%
Pricing
$180/2 mg | $285/5 mg | $420/10 mg | $1,840/5x10 mg
Chemical Structure
HOI-07, Inhibitor (Cat# AAA3841291)
Full Name
HOI-07
Purity
>98%
Pricing
$570/5 mg | $1,030/10 mg | $2,920/50 mg
Testing Data
Reversine, Inhibitor (Cat# AAA516352)
Full Name
Reversine
Purity
>98% (HPLC, TLC); NMR (conforms)
Pricing
$180/1 mg | $275/5 mg | $1,010/5x5 mg
Chemical Structure
AZD1152, Inhibitor (Cat# AAA3840772)
Full Name
AZD1152
Purity
>98%
Pricing
$395/20 mg | $595/50 mg | $1,110/100 mg | $4,935/5x100 mg
Chemical Structure
PF-03814735, Inhibitor (Cat# AAA386651)
Full Name
PF-03814735
Purity
>98%
Pricing
$170/5 mg | $235/10 mg | $740/50 mg | $1,435/100 mg | $6,400/5x100 mg
Structure
SP-146, Inhibitor (Cat# AAA5759466)
Full Name
SP-146
Purity
98.00%
Pricing
$270/1 mg | $415/5 mg | $565/10 mg | $915/25 mg | $1,305/50 mg | $425/1 mL (in DMSO) | $5,595/5x50 mg
Structure
SC-514, Inhibitor (Cat# AAA3604211)
Full Name
SC-514
Purity
>98% (HPLC)
Pricing
$200/10 mg | $230/25 mg | $420/100 mg | $660/200 mg | $2,680/5x200 mg
Structure
ZM-447439, Inhibitor (Cat# AAA3604112)
Full Name
ZM-447439
Purity
>98% (HPLC)
Pricing
$335/50 mg | $1,220/5x50 mg
Structure
CCT129202, Inhibitor (Cat# AAA3606744)
Full Name
CCT129202
Purity
>98% (HPLC)
Pricing
$540/50 mg | $2,120/5x50 mg
Structure
Ilorasertib hydrochloride, Inhibitor (Cat# AAA5753319)
Full Name
Ilorasertib hydrochloride
Purity
98.00%
Pricing
$220/1 mg | $280/5 mg | $355/10 mg | $935/50 mg | $1,480/100 mg | $300/1mL*10mM (in DMSO) | $6,385/5x100 mg
