Filters
Clonality
Type
Reactivity
Gene Name
Isotype
Host
Application
Clone
2677 results for " Bone Metabolism" - showing 50-100
Typical Testing Data/Standard Curve (for reference only)
Bone Morphogenetic Protein 2 (BMP2), ELISA Kit (Cat# AAA2021120)
Full Name
Human Bone Morphogenetic Protein 2 (BMP2) ELISA Kit
Gene Names
BMP2; BDA2; BMP2A
Reactivity
Human
Pricing
$490/48-Strip-Wells | $655/96-Strip-Wells | $2,625/5x96-Strip-Wells | $4,815/10x96-Strip-Wells | $330/24-Strip-Wells
Typical Testing Data/Standard Curve (for reference only)
Growth Differentiation Factor 11 (GDF11), ELISA Kit (Cat# AAA2022680)
Full Name
Human Growth Differentiation Factor 11 (GDF11) ELISA Kit
Gene Names
GDF11; BMP11; BMP-11
Reactivity
Human
Pricing
$535/48-Strip-Wells | $710/96-Strip-Wells | $2,870/5x96-Strip-Wells | $5,220/10x96-Strip-Wells | $345/24-Strip-Wells
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embeded human kidney using MBS7004214 at dilution of 1:100)
Osteopontin, Polyclonal Antibody (Cat# AAA7004214)
Full Name
Rabbit anti-human Osteopontin polyclonal Antibody
Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Reactivity
Human
Applications
EIA, IHC
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Pricing
$180/0.05 mg | $260/0.1 mg | $1,160/5x0.1 mg
Typical Testing Data/Standard Curve (for reference only)
secreted phosphoprotein 1, ELISA Kit (Cat# AAA704337)
Full Name
Rat Osteopontin, OPN ELISA Kit
Gene Names
SPP1; OPN
Reactivity
Rat
Pricing
$470/48-Strip-Wells | $665/96-Strip-Wells | $265/24-Strip-Wells (LIMIT 1) | $2,750/5x96-Strip-Wells | $5,230/10x96-Strip-Wells
Typical Testing Data/Standard Curve (for reference only)
Calreticulin (CRT), ELISA Kit (Cat# AAA2023038)
Full Name
Human Calreticulin (CRT) ELISA Kit
Gene Names
CALR; RO; CRT; SSA; cC1qR; HEL-S-99n
Reactivity
Human
Pricing
$510/48-Strip-Wells | $685/96-Strip-Wells | $2,745/5x96-Strip-Wells | $5,005/10x96-Strip-Wells | $340/24-Strip-Wells
Typical Testing Data/Standard Curve (for reference only)
Procollagen I N-Terminal Propeptide (PINP), ELISA Kit (Cat# AAA2019136)
Full Name
Rat Procollagen I N-Terminal Propeptide (PINP) ELISA Kit
Reactivity
Rat
Pricing
$550/48-Strip-Wells | $740/96-Strip-Wells | $2,985/5x96-Strip-Wells | $5,445/10x96-Strip-Wells | $355/24-Strip-Wells
Typical Testing Data/Standard Curve (for reference only)
Collagen Type XV (COL15), ELISA Kit (Cat# AAA2022002)
Full Name
Human Collagen Type XV (COL15) ELISA Kit
Reactivity
Human
Pricing
$535/48-Strip-Wells | $710/96-Strip-Wells | $2,870/5x96-Strip-Wells | $5,220/10x96-Strip-Wells | $345/24-Strip-Wells
Typical Testing Data/Standard Curve (for reference only)
Bone Sialoprotein (BSP), ELISA Kit (Cat# AAA2023401)
Full Name
Human Bone Sialoprotein (BSP) ELISA Kit
Reactivity
Human
Pricing
$510/48-Strip-Wells | $685/96-Strip-Wells | $2,745/5x96-Strip-Wells | $5,005/10x96-Strip-Wells | $340/24-Strip-Wells
Western Blot (WB)
(Western Blot: Sample: Recombinant ACTb, Human.)
Actin Beta (ACTb), Monoclonal Antibody (Cat# AAA2034680)
Full Name
Anti-Actin Beta (ACTb) Monoclonal Antibody
Gene Names
ACTB; BRWS1; PS1TP5BP1
Reactivity
Human
Applications
WB
Purity
Protein A + Protein G affinity chromatography
Pricing
$180/0.1 mL | $220/0.2 mL | $390/0.5 mL | $475/1 mL | $1,320/5x1 mL
Activity Data
(Figure. The binding activity of RANKL with PPARg.Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a protein that in humans is encoded by the TNFSF11 gene. RANKL is a member of the tumor necrosis factor (TNF) cytokine family, it binds to RANK on cells of the myeloid lineage and functions as a key factor for osteoclast differentiation and activation. It may also bind to osteoprotegerin, a protein secreted mainly by cells of the osteoblast lineage which is a potent inhibitor of osteoclast formation by preventing binding of RANKL to RANK. RANKL also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. This protein was shown to be a dendritic cell survival factor and is involved in the regulation of T cell-dependent immune response. Besides, Peroxisome Proliferator Activated Receptor Gamma (PPARg) has been identified as an interactor of RANKL, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse RANKL and recombinant mouse PPARg. Briefly, RANKL were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to PPARg-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-RANKL pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of RANKLand PPARg was shown in Figure 1, and this effect was in a dose dependent manner.)
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL), Active Protein (Cat# AAA2105122)
Full Name
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
Gene Names
Tnfsf11; ODF; OPGL; RANKL; Ly109l; Trance
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$225/0.01 mg | $490/0.05 mg | $755/0.1 mg | $940/0.2 mg | $1,830/0.5 mg | $2,710/1 mg | $6,620/5 mg
Activity Data
(Matrix Metalloproteinase 13 (MMP13) is a member of the matrix metalloproteinase (MMP) family. MMP13 has been proposed to participate in aggrecan degradation associated with osteoarthritis and cleavage of type II collagen in osteoarthritic cartilage explants and in tumor progression and metastasis. In addition, it can cleave type I, III, IV, IX, X and XIV collagens and fibronectin. MMP13 is likely to play a crucial role in the modulation of extracellular matrix degradation and cell-matrix interactions. Although gelatin zymography is mainly used for the detection of the MMP2 and MMP9, it also can be used for MMP13 dection. Briefly, various concentrations of MMP13 (1000ng, 500ng, 250ng, 125ng) were denatured by SDS loading buffer, electrophoresed through sodium dodecylsulphat- polyacrylamide gel (SDS-PAGE; 10% gels) containing gelatin (1mg/mL) with nonreducing conditions. After renaturation, incubation and CCB-stained, active MMP13 would hydrolyze gelatin nearby, which was indicated by the white bands on the gel. In this experiment we use heat-denatured MMP13 protein as negative control, and blood sample as positive control. Result: Gelatin hydrolysis by recombinant rat MMP13 was shown in figure 1.)
Matrix Metalloproteinase 13 (MMP13), Active Protein (Cat# AAA2097264)
Full Name
Active Matrix Metalloproteinase 13 (MMP13)
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$265/0.01 mg | $595/0.05 mg | $920/0.1 mg | $1,135/0.2 mg | $2,240/0.5 mg | $3,315/1 mg | $8,120/5 mg
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human Lung Tissue; Lane3: Human K562 Cells; Lane4: Mouse Lung Tissue.)
Actin Beta (ACTb), Polyclonal Antibody (Cat# AAA2034679)
Full Name
Anti-Actin Beta (ACTb) polyclonal Antibody
Gene Names
ACTB; BRWS1; PS1TP5BP1
Reactivity
Human
Applications
WB
Purity
Antigen-specific affinity chromatography
Pricing
$165/0.1 mL | $210/0.2 mL | $350/0.5 mL | $430/1 mL | $1,235/5x1 mL
Activity Data
(Figure. The binding activity of OC with FUR.Osteocalcin (OC), also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein hormone found in bone and dentin. Osteocalcin is secreted solely by osteoblasts and thought to play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building, by nature. It is also implicated in bone mineralization and calcium ion homeostasis. Osteocalcin acts as a hormone in the body, causing beta cells in the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Besides, Furin (FUR) has been identified as an interactor of OC, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse OC and recombinant mouse FUR. Briefly, OC were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100mul were then transferred to FUR-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-OC pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of OC and FUR was shown in Figure 1, and this effect was in a dose dependent manner.)
Osteocalcin (OC), Active Protein (Cat# AAA2105093)
Full Name
Active Osteocalcin (OC)
Gene Names
Bglap; OC; BGP; OG1; mOC-A; Bglap1
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$225/0.01 mg | $490/0.05 mg | $755/0.1 mg | $940/0.2 mg | $1,830/0.5 mg | $2,710/1 mg | $6,620/5 mg
Activity Data
(PTH (Parathyroid hormone) is a hormone secreted by the parathyroid glands that is important in bone remodeling. As reported, osteoblast-like cell lines, such as ROS 17/2.8, UMR106, SaOS, U2OS, MG63, that exhibit PTHR1, respond with increased proliferation to PTH. Rat PTH shares similarities with human PTH in amino acid sequence with the identity of 71.3%. Thus, a proliferation assay of rat recombinant PTH was conducted using U2OS cells. Briefly, U2OS cells were seeded into triplicate wells of 96-well plates at a density of 2,000 cells/well and allowed to attach overnight, then the medium was replaced with serum-free standard DMEM prior to the addition of various concentrations of PTH. After incubated for 48h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Proliferation of U2OS cells after incubation with PTH for 48h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8 ) assay after incubation with recombinant PTH for 48h. The result was shown in Figure 2. It was obvious that PTH increased cell viability of U2OS cells.)
Parathyroid Hormone (PTH), Active Protein (Cat# AAA2097252)
Full Name
Active Parathyroid Hormone (PTH)
Gene Names
Pth; Pth1; Pthr1; PTH-(1-84)
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$175/0.01 mg | $330/0.05 mg | $505/0.1 mg | $620/0.2 mg | $1,195/0.5 mg | $1,775/1 mg | $4,350/5 mg
Typical Testing Data/Standard Curve (for reference only)
Noggin (NOG), ELISA Kit (Cat# AAA2024824)
Full Name
Human Noggin (NOG) ELISA Kit
Gene Names
NOG; SYM1; SYNS1
Reactivity
Human
Pricing
$540/48-Strip-Wells | $730/96-Strip-Wells | $2,935/5x96-Strip-Wells | $5,345/10x96-Strip-Wells | $350/24-Strip-Wells
Activity Data
(IL7 (Interleukin 7) is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. The interaction between IL17 and the IL7 receptor triggers a cascade of signals important for T-cell development within the thymus and survival within the periphery. It is reported that IL-7 acts on both resting and activated T cells, including Jurkat cells. Thus, a proliferation assay of recombinant human IL7 was conducted using Jurkat cells. Briefly, Jurkat cells were seeded into triplicate wells of 96-well plates at a density of 10, 000 cells/well in RPMI-1640 with the addition of various concentrations of IL7. After incubated for 72h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Cell proliferation of Jurkat cells after incubation with IL7 for 72h observed by inverted microscope was shown in Figure 1. The CCK-8 data was shown in Figure 2. It was obvious that IL7 significantly promoted cell proliferation of Jurkat cells.)
Interleukin 7 (IL7), Active Protein (Cat# AAA2097240)
Full Name
Active Interleukin 7 (IL7)
Gene Names
IL7; IL-7
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$240/0.01 mg | $510/0.05 mg | $795/0.1 mg | $985/0.2 mg | $1,920/0.5 mg | $2,840/1 mg | $6,945/5 mg
Typical Testing Data/Standard Curve (for reference only)
Actin Beta (ACTb), ELISA Kit (Cat# AAA2025077)
Full Name
Human Actin Beta (ACTb) ELISA Kit
Gene Names
actb; B-actin; beta-actin
Reactivity
Human
Pricing
$525/48-Strip-Wells | $695/96-Strip-Wells | $2,810/5x96-Strip-Wells | $5,125/10x96-Strip-Wells | $345/24-Strip-Wells
Activity Data
(Macrophage Colony Stimulating Factor (M-CSF), also known as CSF-1,is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. It can also affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy. Besides, Colony Stimulating Factor Receptor, Macrophage (M-CFS-R) has been identified as an interactor of M-CSF, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse M-CSF and recombinant mouse MCFSR Briefly, M-CSF were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to M-CFS-R-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-M-CSF pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of M-CSF and M-CFS-R was shown in Figure 1, and this effect was in a dose dependent manner.)
Colony Stimulating Factor 1, Macrophage (MCSF), Active Protein (Cat# AAA2097263)
Full Name
Active Colony Stimulating Factor 1, Macrophage (MCSF)
Gene Names
Csf1; op; Csfm; MCSF; C87615
Reactivity
Mouse
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$205/0.01 mg | $415/0.05 mg | $635/0.1 mg | $790/0.2 mg | $1,530/0.5 mg | $2,280/1 mg | $5,565/5 mg
Sequence
Procollagen I N-Terminal Propeptide (PINP), Peptide (Cat# AAA2097741)
Full Name
Synthetic Procollagen I N-Terminal Propeptide (PINP)
Gene Names
Col1a1; Cola1; Mov13; Cola-1; Mov-13; Col1a-1
Applications
Immunogen; Blocking Peptide
Purity
>95%
Pricing
$140/0.01 mg | $240/0.05 mg | $345/0.1 mg | $425/0.2 mg | $805/0.5 mg | $1,180/1 mg | $2,885/5 mg | $12,970/5x5 mg
CD13 / Aminopeptidase-N, Monoclonal Antibody (Cat# AAA439048)
Full Name
CD13 / Aminopeptidase-N (Myeloid Cell Marker) Mouse Monoclonal Antibody
Gene Names
ANPEP; APN; CD13; LAP1; P150; PEPN; GP150
Reactivity
Human
Applications
FC/FACS, IF, IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Western Blot (WB)
(Leptin Receptor (LEPR) Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LEPR antibody detected the LEPR protein (arrow).)
Leptin Receptor (LEPR), Polyclonal Antibody (Cat# AAA9204850)
Full Name
Leptin Receptor (LEPR) Antibody (N-term)
Gene Names
LEPR; OBR; OB-R; CD295; LEP-R; LEPRD
Reactivity
Human
Applications
WB, EIA, FC/FACS, IHC-P
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Activity Data
(PTHrP (Parathyroid Hormone Related Protein ) is a neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. A binding ELISA assay was conducted to detect the association of PTHrP with PTHR1. Briefly, PTHrP were diluted serially in PBS, with 0.01%BSA (pH 7.4). Duplicate samples of 100uL PTHrP were then transferred to PTHR1-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PTHrP pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PTHrP and PTHR1 was shown in Figure 1, and this effect was in a dose dependent manner.)
Parathyroid Hormone Related Protein (PTHrP), Active Protein (Cat# AAA2097284)
Full Name
Active Parathyroid Hormone Related Protein (PTHrP)
Gene Names
Pthlh; PLP; Pthrp; PTH-like
Reactivity
Mouse
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$225/0.01 mg | $475/0.05 mg | $735/0.1 mg | $910/0.2 mg | $1,775/0.5 mg | $2,625/1 mg | $6,415/5 mg
Typical Testing Data/Standard Curve (for reference only)
Osteopontin (OPN), ELISA Kit (Cat# AAA2024631)
Full Name
Human Osteopontin (OPN) ELISA Kit
Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Reactivity
Human
Pricing
$385/48-Strip-Wells | $515/96-Strip-Wells | $2,065/5x96-Strip-Wells | $3,790/10x96-Strip-Wells | $280/24-Strip-Wells
Sequence
Asporin (ASPN), Active Protein (Cat# AAA2105172)
Full Name
Active Asporin (ASPN)
Gene Names
Aspn; Plap1; Slrr1c; AA986886; 4631401G09Rik
Reactivity
Mus musculus (Mouse)
Applications
Cell culture; Activity Assays.
Purity
>95%
Pricing
$210/0.01 mg | $435/0.05 mg | $665/0.1 mg | $825/0.2 mg | $1,600/0.5 mg | $2,385/1 mg | $5,820/5 mg
Activity Data
(Figure. Cell proliferation of TF-1 cells after stimulated with LIF.Leukemia Inhibitory Factor (LIF), is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. p53 regulated LIF has been shown to facilitate implantation in the mouse model and possibly in humans. To test the effect of LIF on cell proliferation, TF-1 cells were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well with 1% serum standard 1640 including various concentrations of recombinant human LIF. After incubated for 72h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Proliferation of TF-1 cells after incubation with LIF for 72h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8 ) assay after incubation with recombinant LIF for 72h. The result was shown in Figure 2. It was obvious that LIF significantly increased cell viability of TF-1 cells.(A) TF-1 cells cultured in 1640, stimulated with 0.5ng/mL LIF for 72h; (B) Unstimulated TF-1 cells cultured in 1640 for 72h.)
Leukemia Inhibitory Factor (LIF), Active Protein (Cat# AAA2097262)
Full Name
Active Leukemia Inhibitory Factor (LIF)
Gene Names
LIF; CDF; DIA; HILDA; MLPLI
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$165/0.01 mg | $310/0.05 mg | $480/0.1 mg | $585/0.2 mg | $1,120/0.5 mg | $1,660/1 mg | $4,075/5 mg
Activity Data
(NOG (Noggin) is a signaling molecule that plays an important role in promoting somite patterning in the developing embryo, essential for cartilage morphogenesis and joint formation. It is considered as an inhibitor in bone morphogenetic proteins (BMP) signaling, by binding with BMP4, thus a binding ELISA assay was conducted to detect the association of recombinant rat NOG with BMP4. Briefly, NOG were diluted serially in PBS with 0.01%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to BMP4-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-NOG pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of NOG with BMP4 was shown in Figure 1 and this effect was in a dose dependent manner.)
Noggin (NOG), Active Protein (Cat# AAA2097352)
Full Name
Active Noggin (NOG)
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$205/0.01 mg | $420/0.05 mg | $645/0.1 mg | $800/0.2 mg | $1,550/0.5 mg | $2,310/1 mg | $5,640/5 mg
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human liver using MPO Polyclonal Antibody at dilution of 1:300.)
MPO, Polyclonal Antibody (Cat# AAA2556112)
Full Name
MPO Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
IHC, IF
Purity
Affinity Purification
Pricing
$405/0.2 mL | $255/0.12 mL | $180/0.06 mL | $1,825/5x0.2 mL
CD13 / Aminopeptidase-N, Monoclonal Antibody (Cat# AAA439496)
Full Name
CD13 / Aminopeptidase-N (Myeloid Cell Marker) Mouse Monoclonal Antibody
Gene Names
ANPEP; APN; CD13; LAP1; P150; PEPN; GP150
Reactivity
Human
Applications
FC/FACS, IF, IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Western Blot (WB)
(Western blot analysis of SGMS2 Antibody (C-term) (MBS9201412) in HepG2 cell line lysates (35ug/lane). SGMS2 (arrow) was detected using the purified Pab.)
SGMS2, Polyclonal Antibody (Cat# AAA9201412)
Full Name
SGMS2 Antibody (C-term)
Gene Names
SGMS2; SMS2
Reactivity
Human, mouse (Predicted Reactivity: Monkey, Rat)
Applications
WB, EIA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Typical Testing Data/Standard Curve (for reference only)
Actin Beta (ACTb), CLIA Kit (Cat# AAA2025259)
Full Name
Human Actin Beta (ACTb) CLIA Kit
Reactivity
Human
Pricing
$630/48-Strip-Wells | $855/96-Strip-Wells | $3,430/5x96-Strip-Wells | $6,220/10x96-Strip-Wells | $405/24-Strip-Wells
CD13 / Aminopeptidase-N, Monoclonal Antibody (Cat# AAA439675)
Full Name
CD13 / Aminopeptidase-N (Myeloid Cell Marker) Mouse Monoclonal Antibody
Gene Names
ANPEP; APN; CD13; LAP1; P150; PEPN; GP150
Reactivity
Human
Applications
FC/FACS, IF, IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Activity Data
(Platelet Derived Growth Factor Subunit A (PDGFA) is a member of Platelet-derived growth factor (PDGF) family which plays a significant role in blood vessel formation, the growth of blood vessels from already-existing blood vessel tissue, mitogenesis, i.e. proliferation, of mesenchymal cells such as fibroblasts, osteoblasts, tenocytes, vascular smooth muscle cells and mesenchymal stem cells as well as chemotaxis, the directed migration, of mesenchymal cells. Besides, Platelet Derived Growth Factor Receptor Alpha (PDGFRa) has been identified as an interactor of PDGFA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PDGFA and recombinant human PDGFRa. Briefly, PDGFA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100mul were then transferred to PDGFRa-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PDGFA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PDGFA and PDGFRa was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of PDGFA with PDGFRa.)
Platelet Derived Growth Factor Subunit A (PDGFA), Active Protein (Cat# AAA2105097)
Full Name
Active Platelet Derived Growth Factor Subunit A (PDGFA)
Gene Names
PDGFA; PDGF1; PDGF-A
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$225/0.01 mg | $475/0.05 mg | $735/0.1 mg | $910/0.2 mg | $1,775/0.5 mg | $2,625/1 mg | $6,415/5 mg
Testing Data(TD)
(All lanes : Anti-ATG7 Antibody (C-term) at1:500 dilution Lane 1: Caki-1 whole cell lysateLane 2: Hela whole cell lysate Lane 3: HepG2whole cell lysate Lysates/proteins at 40 µg perlane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 78 kDa Blocking/Dilutionbuffer: 5% NFDM/TBST.)
ATG7, Polyclonal Antibody (Cat# AAA9204169)
Full Name
ATG7 Antibody (C-term)
Gene Names
ATG7; GSA7; APG7L; APG7-LIKE
Reactivity
Human, Mouse
Predicted reactivity: Chicken, Rat
Predicted reactivity: Chicken, Rat
Applications
WB, EIA, IHC, IF
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Sequence Information
Procollagen III N-Terminal Propeptide (PIIINP), Peptide (Cat# AAA2097735)
Full Name
Synthetic Procollagen III N-Terminal Propeptide (PIIINP)
Gene Names
Col3a1; Tsk2; Tsk-2; Col3a-1; AW550625
Reactivity
Mouse
Applications
Immunogen, Blocking Peptide
Purity
> 95%
Pricing
$135/0.01 mg | $225/0.05 mg | $320/0.1 mg | $400/0.2 mg | $760/0.5 mg | $1,115/1 mg | $2,710/5 mg | $12,190/5x5 mg
Activity Data
(GDF9 (Growth/differentiation factor 9) is an oocyte derived growth factora which belongs to the transforming growth factor-beta (TGFbeta) superfamily. GDF9 is required for ovarian folliculogenesis and promotes primordial follicle development. S100A8 has been identified as an interactor of GDF9 through two-hybrid assay, thus a binding ELISA assay was conducted to detect the interaction of recombinant human GDF9 and recombinant human S100A8. Briefly, GDF9 were diluted serially in PBS, with 0.01%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to S100A8-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-GDF9 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of GDF9 and S100A8 was shown in Figure 1, and this effect was in a dose dependent manner.)
Growth Differentiation Factor 9 (GDF9), Active Protein (Cat# AAA2097272)
Full Name
Active Growth Differentiation Factor 9 (GDF9)
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$240/0.01 mg | $520/0.05 mg | $800/0.1 mg | $995/0.2 mg | $1,940/0.5 mg | $2,875/1 mg | $7,030/5 mg
Testing Data
(Peptide-+)
BMX, Antibody (Cat# AAA855056)
Full Name
BMX Antibody
Gene Names
BMX; ETK; PSCTK2; PSCTK3
Reactivity
Human, Mouse
Applications
WB, IHC, IF, EIA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$310/0.1 mg | $1,330/5x0.1 mg | $465/0.1 mL (Biotin) | $465/0.1 mL (FITC) | $465/0.1 mL (AF350) | $465/0.1 mL (AF405) | $465/0.1 mL (AF488) | $465/0.1 mL (AF555) | $465/0.1 mL (AF568)
Activity Data
(Figure. The binding activity of COL6a1 with PDGFA.Collagen alpha-1(VI) chain (COL6a1) is a protein that in humans, the collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Besides, Platelet-derived growth factor subunit A (PDGFA) has been identified as an interactor of COL6A1, thus a binding ELISA assay was conducted to detect the interaction of recombinant human COL6a1 and recombinant human PDGFA. Briefly, COL6a1 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to PDGFA-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-COL6a1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of COL6a1 and PDGFA was shown in Figure 1, and this effect was in a dose dependent manner.)
Collagen Type VI Alpha 1 (COL6a1), Active Protein (Cat# AAA2105169)
Full Name
Active Collagen Type VI Alpha 1 (COL6a1)
Gene Names
Col6a1; Col6a-1; AI747156
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$225/0.01 mg | $490/0.05 mg | $755/0.1 mg | $940/0.2 mg | $1,830/0.5 mg | $2,710/1 mg | $6,620/5 mg
Western Blot (WB)
(Western blot analysis of anti-BMPR1A Antibody (N-term K36) in 293 cell line lysates (35ug/lane). BMPR1A(arrow) was detected using the purified Pab.)
BMPR1A, Polyclonal Antibody (Cat# AAA9204829)
Full Name
BMPR1A Antibody (N-term K36)
Gene Names
BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del
Reactivity
Human
Applications
WB, EIA, IF, IHC
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Activity Data
(CA2 (Carbonic anhydrase 2) is an enzyme that catalyzes reversible hydration of carbon dioxide. It is essential for bone resorption and osteoclast differentiation and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. It is widely accepted that CA2 also catalyzes hydrolysis of p-Nitrophenyl Acetate. Thus, a hydration assay was conducted to test the catalytic activity of CA2 using 4-Nitrophenyl Acetate (4-NPA) as substrate. Briefly, different concentrations of CA2 were incubated with 1mM 4-NPA in reaction buffer. The absorbance at the wavelength of 400nm was read per hour, and the result was shown in figure 1. It is obvious that CA2 catalyzes hydrolysis of p-Nitrophenyl Acetate.)
Carbonic Anhydrase II (CA2), Active Protein (Cat# AAA2097353)
Full Name
Active Carbonic Anhydrase II (CA2)
Gene Names
Car2; Ca2
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$145/0.01 mg | $250/0.05 mg | $365/0.1 mg | $450/0.2 mg | $850/0.5 mg | $1,250/1 mg | $3,055/5 mg | $13,745/5x5 mg
Activity Data
(Interleukin-6 (IL-6), a pro-inflammatory cytokine and an anti-inflammatory myokine, plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It has been reported that IL-6 significantly increased the MMP-10 protein lever in the human lung cancer A549 cells through the JAK/STAT signaling pathway. Briefly, A549 cells were seeded into 6-well cell culture clusters and allowed to grow to 50-70% confluence, then different concentrations of IL-6 was added. After incubated for 24h, the protein levels of MMP-10 in the cell supernatant were determined by Western blot.Result: MMP-10 protein lever significantly increased in A549 cells due to the stimulation of IL-6, the data was shown in Figure 1.)
Interleukin 6 (IL6), Active Protein (Cat# AAA2097342)
Full Name
Active Interleukin 6 (IL6)
Gene Names
Il6; ILg6; Ifnb2
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$215/0.01 mg | $450/0.05 mg | $690/0.1 mg | $850/0.2 mg | $1,660/0.5 mg | $2,470/1 mg | $6,035/5 mg
Activity Data
(Figure. The binding activity of NOG with CDF5.Noggin, also known as NOG, is a protein that is involved in the development of many body tissues, including nerve tissue, muscles, and bones. Noggin is a signaling molecule that plays an important role in promoting somite patterning in the developing embryo. It is released from the notochord and regulates bone morphogenic protein (BMP4) during development. It also causes formation of the head and other dorsal structures. Besides, Growth Differentiation Factor 5 (GDF5) has been identified as an interactor of NOG, thus a binding ELISA assay was conducted to detect the interaction of recombinant human NOG and recombinant human CDF5. Briefly, NOG were diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to CDF5-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-NOG pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of NOG and CDF5 was shown in Figure 1, and this effect was in a dose dependent manner.)
Noggin (NOG), Active Protein (Cat# AAA2105168)
Full Name
Active Noggin (NOG)
Gene Names
NOG; SYM1; SYNS1; SYNS1A
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$185/0.01 mg | $360/0.05 mg | $555/0.1 mg | $680/0.2 mg | $1,320/0.5 mg | $1,960/1 mg | $4,820/5 mg
SDS-Page
(SDS-PAGE Analysis Purified CD13 Mouse Monoclonal Antibody (APN/1464). Confirmation of Integrity and Purity of Antibody.)
CD13/Aminopeptidase-N, Monoclonal Antibody (Cat# AAA4380954)
Full Name
CD13/Aminopeptidase-N (Myeloid Cell Marker)
Gene Names
ANPEP; APN; CD13; LAP1; P150; PEPN; GP150
Reactivity
Human
Applications
EIA
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Calcitonin, ELISA Kit (Cat# AAA494282)
Full Name
Calcitonin ELISA
Gene Names
CALCA; CT; KC; CGRP; CALC1; CGRP1; CGRP-I
Reactivity
Human
Pricing
$670/96 Tests | $3,085/5x96 Tests
Activity Data
(Figure1. TRAP levels in the cell of RAW264.7 cells induced by RANKL.Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a member of the tumor necrosis factor (TNF) superfamily. RANKL has been identified to affect the immune system and control bone regeneration and remodeling. RANKL is an apoptosis regulator gene, a binding partner of osteoprotegerin (OPG), a ligand for the receptor RANK and controls cell proliferation by modifying protein levels of Id4, Id2 and cyclin D1. The protein can bind to RANK on cells of the myeloid lineage and functions as a key factor for osteoclast differentiation and activation. Thus, we use recombinant RANKL to induce RAW264.7 mouse monocyte/macrophage cells to differentiate to osteoclast cell. RAW264.7 mouse monocyte/macrophage cells were seeded into 24-well plates at a density of 2×105 and allowed to attach overnight, then treated with RANKL (1ng/mL, 10ng/mL) and incubated for 72h. Then we assay TRAP (a kind of enzyme expressed by osteoclast cell) by ELASA. Result: TRAP levels in the cell supernatant of RAW264.7 cells increased significantly after stimulated with RANK, the data was shown in Table 1 and Figure1.)
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL), Active Protein (Cat# AAA2105123)
Full Name
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
Gene Names
Tnfsf11; ODF; OPGL; RANKL; Ly109l; Trance
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$230/0.01 mg | $505/0.05 mg | $780/0.1 mg | $970/0.2 mg | $1,890/0.5 mg | $2,800/1 mg | $6,840/5 mg
Activity Data
(BMP4 (Bone morphogenetic protein 4) is a member of the bone morphogenetic protein family, which is involved in bone and cartilage development, specifically tooth and limb development and fracture repair. It has been proven that HJV (Hemojuvelin) acts as a coreceptor of BMPs, including BMP4; therefore, a binding ELISA assay was constructed to detect the association of recombinant human BMP4 with recombinant human HJV. Briefly, BMP4 were diluted serially in PBS, with 0.01%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to HJV-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-BMP4 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of BMP4 with HJV was shown in Figure 1 and this effect was in a dose dependent manner.)
Bone Morphogenetic Protein 4 (BMP4), Active Protein (Cat# AAA2097338)
Full Name
Active Bone Morphogenetic Protein 4 (BMP4)
Gene Names
BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$230/0.01 mg | $505/0.05 mg | $780/0.1 mg | $970/0.2 mg | $1,890/0.5 mg | $2,800/1 mg | $6,840/5 mg
Sequence
Collagen Type VI Alpha 1 (COL6a1), Active Protein (Cat# AAA2105170)
Full Name
Active Collagen Type VI Alpha 1 (COL6a1)
Gene Names
Col6a1; Col6a-1; AI747156
Reactivity
Mus musculus (Mouse)
Applications
Cell culture; Activity Assays.
Purity
>95%
Pricing
$225/0.01 mg | $490/0.05 mg | $755/0.1 mg | $940/0.2 mg | $1,830/0.5 mg | $2,710/1 mg | $6,620/5 mg
Western Blot (WB)
(Figure 1: Western blot analysis using BMX mAb against BMX-hIgGFc transfected HEK293 cell lysate.)
BMX, Antibody (Cat# AAA850242)
Full Name
BMX Antibody
Gene Names
BMX; ETK; PSCTK2; PSCTK3
Reactivity
Human
Applications
WB, EIA
Pricing
$310/0.1 mg | $1,330/5x0.1 mg | $570/0.1 mL (Biotin) | $570/0.1 mL (FITC) | $570/0.1 mL (AF350) | $570/0.1 mL (AF405) | $570/0.1 mL (AF488) | $570/0.1 mL (AF555) | $570/0.1 mL (AF568)
Activity Data
(Figure. The binding activity of DKK1 with CTNNb1.)
Dickkopf Related Protein 1 (DKK1), Active Protein (Cat# AAA2097279)
Full Name
Active Dickkopf Related Protein 1 (DKK1)
Gene Names
DKK1; SK; DKK-1
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$230/0.01 mg | $500/0.05 mg | $775/0.1 mg | $960/0.2 mg | $1,870/0.5 mg | $2,770/1 mg | $6,775/5 mg
Activity Data
(Figure. The binding activity of TNFRSF11A with TRAF5.RANK tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A) also known as receptor Activator of Nuclear Factor kappa B (RANK) or TRANCE Receptoris a member of the tumor necrosis factor receptor (TNFR) molecular sub-family. TNFRSF11A is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It is associated with bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. Besides, TNF Receptor Associated Factor 5 (TRAF5) has been identified as an interactor of TNFRSF11A, thus a binding ELISA assay was conducted to detect the interaction of recombinant human TNFRSF11A and recombinant human TRAF5. Briefly, TNFRSF11A were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to TRAF5-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-TNFRSF11A pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TNFRSF11A and TRAF5 was shown in Figure 1, and this effect was in a dose dependent manner.)
Receptor Activator Of Nuclear Factor Kappa B (RANk), Active Protein (Cat# AAA2105163)
Full Name
Active Receptor Activator Of Nuclear Factor Kappa B (RANk)
Gene Names
TNFRSF11A; FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1
Applications
Cell Culture, Activity Assays
Purity
> 97%
Pricing
$225/0.01 mg | $480/0.05 mg | $740/0.1 mg | $915/0.2 mg | $1,790/0.5 mg | $2,645/1 mg | $6,465/5 mg
Sequence Information
Cross Linked C-Telopeptide Of Type II Collagen (CTXII), Peptide (Cat# AAA2097736)
Full Name
Synthetic Cross Linked C-Telopeptide Of Type II Collagen (CTXII)
Gene Names
COL2A1; AOM; ANFH; SEDC; STL1; COL11A3
Reactivity
Human
Applications
Immunogen, Blocking Peptide
Purity
> 95%
Pricing
$140/0.01 mg | $230/0.05 mg | $335/0.1 mg | $415/0.2 mg | $780/0.5 mg | $1,145/1 mg | $2,800/5 mg | $12,580/5x5 mg
