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153 results for "Src inhibitor" - showing 1-50
Western Blot (WB)
(Western blot analysis of extracts from HepG2 using SNIP antibody.)
SNIP, Polyclonal Antibody (Cat# AAA9606177)
Full Name
SNIP Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Protein Kinase C Inhibitor, zeta, Pseudosubstrate, Myristoylated, Inhibitor (Cat# AAA655385)
Full Name
Protein Kinase C Inhibitor, zeta, Pseudosubstrate, Myristoylated
Gene Names
SRC; ASV; SRC1; c-SRC; p60-Src
Purity
Highly Purified
~90% by HPLC and MS analysis
~90% by HPLC and MS analysis
Pricing
$325/1 mg | $1,460/5x1 mg
Testing Data #2
(Western blot analysis of extracts from HepG2 and HeLa cells, using SNIP antibody.)
SNIP, Antibody (Cat# AAA853345)
Full Name
SNIP Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$310/0.1 mg | $1,330/5x0.1 mg | $465/0.1 mL (Biotin) | $465/0.1 mL (FITC) | $465/0.1 mL (AF350) | $465/0.1 mL (AF405) | $465/0.1 mL (AF488) | $465/0.1 mL (AF555) | $465/0.1 mL (AF568)
Western Blot (WB)
(Western blot analysis of p140 Cap expression in HEK293T (A), HeLa (B) whole cell lysates.)
p140 Cap, Polyclonal Antibody (Cat# AAA8221699)
Full Name
Anti-p140 Cap Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB
Purity
The antibody was purified by immunogen affinity chromatography.
Pricing
$175/0.03 mL | $245/0.1 mL | $325/0.2 mL | $1,410/5x0.2 mL
Structure
Baricitinib, Inhibitor (Cat# AAA576687)
Full Name
Baricitinib (LY3009104, INCB028050)
Purity
98.9%
Pricing
$185/2 mg | $195/5 mg | $205/10 mg | $230/25 mg | $245/50 mg | $270/100 mg | $195/1 mL (in DMSO) | $950/5x100 mg
Testing Data
(Activity was measured by titrating 23ng of p27 protein complex in a ubiquitination assay. Data shown for a representative lot. (Shown for reference))
p27 Complex, Activated, Recombinant Protein (Cat# AAA636091)
Full Name
p27 Complex, Activated, Recombinant, Human (p27kip1, Cyclin-dependent kinase inhibitor 1B, Kip1)
Gene Names
Inpp5d; SHIP; SHIP1; SHIP-1; s-SHIP; AI323613
Purity
Highly Purified
~94.6% (SDS-PAGE and Coomassie blue staining)
~94.6% (SDS-PAGE and Coomassie blue staining)
Pricing
$1,170/0.01 mg | $5,265/5x0.01 mg
SU6656, Inhibitor (Cat# AAA579514)
Full Name
SU6656
Purity
97.00%
Pricing
$195/2 mg | $230/5 mg | $275/10 mg | $405/25 mg | $635/50 mg | $800/100 mg | $230/1 mL (in DMSO) | $3,340/5x100 mg
Molecular Structure
Src I1, Inhibitor (Cat# AAA515021)
Full Name
Src I1
Purity
98% (TLC; 5% CH3OH in CH2Cl2; Rf=0.43); NMR (Conforms)
Pricing
$195/5 mg | $405/25 mg | $1,605/5x25 mg
SRC kinase signaling inhibitor 1 (SRCIN1), Recombinant Protein (Cat# AAA1480399)
Full Name
Recombinant Human SRC kinase signaling inhibitor 1 (SRCIN1) , partial
Gene Names
SRCIN1; P140; SNIP
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
SRC kinase signaling inhibitor 1 (Srcin1), Recombinant Protein (Cat# AAA1354190)
Full Name
Recombinant Rat SRC kinase signaling inhibitor 1 (Srcin1) , partial
Gene Names
Srcin1; P140; Snip
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Western Blot (WB)
(Western Blot analysis of HeLa cells using p140Cap Polyclonal Antibody)
p140Cap, Polyclonal Antibody (Cat# AAA9407966)
Full Name
p140Cap Polyclonal Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$245/0.05 mL | $305/0.1 mL | $1,230/5x0.1 mL
Molecular Structure
Genistein, Inhibitor (Cat# AAA515015)
Full Name
Genistein
Purity
98% (TLC); NMR (Conforms)
Pricing
$165/10 mg | $255/50 mg | $930/5x50 mg
Testing Data
(Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor with IC50 of 0.37, 2, 1.5, 2.2, 1.1, 1and 0.24 nM for native pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRalpha, mutant FLT3 phosphorylation and LYN. It potently inhibited other clinically important ABL kinase domain mutants with IC50 from 0.30 to 0.44 nM and inhibited SRC with an IC50 of 5.4 nM. It inhibits the proliferation of mutant FLT3-positive cells with an IC50 of 13 nM and that inhibits mutant FLT3 phosphorylation with an IC50 of 1 nM and the proliferation of BCR-ABL1 T315I-positive Ba/F3 cells with an IC50 of 8 nM. It inhibited all tested BCR-ABL mutants with low nM IC50s in cellular and biochemical assays, suppressed BCR-ABL(T315I)-driven tumor growth in mice, and completely abrogated resistance in cell-based mutagenesis screens. AP24534 is used for treatment of CML. It did not inhibit Aurora kinase family members, nor did it inhibit insulin receptor or cyclin-dependent kinase 2 (CDK2)/Cyclin E (IC50 > 1000-fold relative to native ABL. [1][2][3])
Ponatinib, Inhibitor (Cat# AAA8506540)
Full Name
Ponatinib (AP24534)
Pricing
$440/10 mg | $1,940/5x10 mg
FGR, Polyclonal Antibody (Cat# AAA1488530)
Full Name
Rabbit Anti Human FGR PolyClonal Antibody
Gene Names
Fgr; p55-Fgr
Reactivity
Human
Applications
WB, IHC
Purity
Affinity Purification
Pricing
$325/0.1 mL | $1,465/5x0.1 mL
Structure
PP2, Inhibitor (Cat# AAA578828)
Full Name
PP2
Purity
95.7%
Pricing
$195/2 mg | $210/5 mg | $250/10 mg | $315/25 mg | $395/50 mg | $615/100 mg | $210/1 mL (in DMSO) | $2,500/5x100 mg
Molecular Structure
GSK-690693 HCl, Inhibitor (Cat# AAA515016)
Full Name
GSK-690693 HCl
Purity
99% (HPLC); NMR (Conforms)
Pricing
$230/5 mg | $550/25 mg | $2,250/5x25 mg
Dasatinib monohydrate, Inhibitor (Cat# AAA575677)
Full Name
Dasatinib monohydrate
Purity
100.0%
Pricing
$195/25 mg | $215/50 mg | $240/100 mg | $305/200 mg | $195/1 mL (in DMSO) | $1,105/5x200 mg
Src, EGF, Non-competitive Inhibitor, Peptide A, Substrate (Cat# AAA639302)
Full Name
Src, EGF, Non-competitive Inhibitor, Peptide A
Purity
Highly Purified
~90% by HPLC and MS analysis
~90% by HPLC and MS analysis
Pricing
$600/1 mg | $2,695/5x1 mg
Western Blot (WB)
(Western blot analysis of extracts from HepG2 and HeLa cells, using SNIP antibody.)
SNIP, Polyclonal Antibody (Cat# AAA9409550)
Full Name
SNIP Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human
Applications
WB
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$245/0.05 mL | $305/0.1 mL | $1,230/5x0.1 mL
p140 Cap, Blocking Peptide (Cat# AAA8204480)
Full Name
p140 Cap Blocking Peptide
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat, Monkey
Applications
BL
Purity
>85%
Pricing
$180/1 mg | $335/5 mg | $1,455/5x5 mg
Chemical Structure
(Chemical structure of PP2 (SIH-470), a Src family kinase inhibitor. CAS #: 172889-27-9. Molecular Formula: C15H16ClN5. Molecular Weight: 301.8 g/mol.)
PP2, Small Molecule (Cat# AAA808170)
Full Name
PP2
Purity
>=98% (TLC)
Pricing
$280/5 mg | $760/25 mg | $3,210/5x25 mg | $1,015/5x5 mg
Molecular Structure
ZM-336372, Inhibitor (Cat# AAA515008)
Full Name
ZM-336372
Purity
>=98% (TLC; 5% CH3OH in CH2Cl2; Rf=0.43); NMR (conforms)
Pricing
$210/5 mg | $425/25 mg | $1,690/5x25 mg
SRC kinase signaling inhibitor 1 (Srcin1), Recombinant Protein (Cat# AAA1395297)
Full Name
Recombinant Mouse SRC kinase signaling inhibitor 1 (Srcin1) , partial
Gene Names
Srcin1; P140; SNIP; p140Cap; mKIAA1684
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Molecular Structure
SU-4312, Inhibitor (Cat# AAA515079)
Full Name
SU-4312
Purity
>98% (TLC); NMR (Conforms)
Pricing
$195/5 mg | $380/25 mg | $1,490/5x25 mg
Chemical Structure
(Chemical structure of Dasatinib (SIH-440), a Src and Bcr/Abl kinase inhibitor. CAS #: 302962-49-8. Molecular Formula: C22H26ClN7O2S. Molecular Weight: 488 g/mol.)
Dasatinib, Small Molecule (Cat# AAA808140)
Full Name
Dasatinib
Purity
>=98%
Pricing
$190/5 mg | $245/25 mg | $885/5x25 mg | $630/5x5 mg
Structure
NVP-BHG712, Inhibitor (Cat# AAA578898)
Full Name
NVP-BHG712
Purity
98.0%
Pricing
$205/2 mg | $225/5 mg | $270/10 mg | $405/25 mg | $645/50 mg | $800/100 mg | $230/1 mL (in DMSO) | $3,330/5x100 mg
SRCIN1, siRNA (Cat# AAA8226451)
Full Name
SRCIN1 siRNA (Mouse)
Gene Names
Srcin1; P140; SNIP; p140Cap; mKIAA1684
Reactivity
Mouse
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
Testing Data
(PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 uM for p110alpha, p110beta, p110delta, p110gamma, DNA-PK, mTOR and PDGFR, respectively. PP121 also inhibits Abl, Hck, Src,Src(T338I), VEGFR2, EGFR EphB4 with IC50 of 0.018, 0.008, 0.014, 0.22, 0.012, 0.26, 0.19 uM, respectively. PP121 exhibits no significant effect on receptor serine/threonine kinases (RSTKs). PP121 blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor. PP121 achieves its dual potency by targeting a residue (Glu310 in Src) that has been structurally conserved between kinase families. PP121 potently and dose-dependently blocked the phosphorylation of Akt, p70S6K and S6 in these cells. [1])
SRCIN1, siRNA (Cat# AAA827764)
Full Name
SRCIN1 siRNA (Human)
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
Testing Data
(Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.)
pp60 c-src, Inhibitor (Cat# AAA8506437)
Full Name
pp60 c-src (521-533) (phosphorylated)
Purity
>99%
Pricing
$325/1 mg | $1,415/5x1 mg
Chemical Structure
(Chemical structure of PP1 (SIH-469), a Src family kinase inhibitor. CAS #: 172889-26-8. Molecular Formula: C16H19N5. Molecular Weight: 281.4 g/mol.)
PP1, Small Molecule (Cat# AAA808169)
Full Name
PP1
Purity
>= 98% (TLC)
Pricing
$250/5 mg | $650/25 mg | $2,700/5x25 mg | $905/5x5 mg
SRCIN1, siRNA (Cat# AAA828389)
Full Name
SRCIN1 siRNA (Rat)
Gene Names
Srcin1; P140; Snip
Reactivity
Rat
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
Structure
PP1, Inhibitor (Cat# AAA578760)
Full Name
PP1
Purity
100.0%
Pricing
$200/2 mg | $230/5 mg | $260/10 mg | $340/25 mg | $405/50 mg | $575/100 mg | $230/1 mL (in DMSO) | $2,330/5x100 mg
Western Blot (WB)
(Western blot analysis of extracts from HepG2 and HeLa cells, using SNIP antibody.)
SNIP, Antibody (Cat# AAA8515427)
Full Name
SNIP Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Immunogen affinity purified
Pricing
$310/0.1 mg | $1,330/5x0.1 mg | $465/0.1 mL (Biotin) | $465/0.1 mL (FITC) | $465/0.1 mL (AF350) | $465/0.1 mL (AF405) | $465/0.1 mL (AF488) | $465/0.1 mL (AF555) | $465/0.1 mL (AF568)
Structure
Saracatinib, Inhibitor (Cat# AAA578651)
Full Name
Saracatinib
Purity
98.03%
Pricing
$195/5 mg | $210/10 mg | $260/25 mg | $290/50 mg | $360/100 mg | $570/200 mg | $205/1 mL (in DMSO) | $2,290/5x200 mg
p140Cap, Polyclonal Antibody (Cat# AAA8524472)
Full Name
p140Cap Polyclonal Antibody
Gene Names
SRCIN1; P140; SNIP
Pricing
$310/0.1 mg | $1,330/5x0.1 mg | $465/0.1 mL (Biotin) | $465/0.1 mL (FITC) | $465/0.1 mL (AF350) | $465/0.1 mL (AF405) | $465/0.1 mL (AF488) | $465/0.1 mL (AF555) | $465/0.1 mL (AF568)
Scutellarein, Inhibitor (Cat# AAA578355)
Full Name
Scutellarein
Purity
98.3%
Pricing
$195/1 mg | $250/5 mg | $305/10 mg | $500/25 mg | $710/50 mg | $250/1 mL (in DMSO) | $2,925/5x50 mg
TPX-0005, Inhibitor (Cat# AAA579971)
Full Name
TPX-0005
Purity
100.0%
Pricing
$205/2 mg | $240/5 mg | $310/10 mg | $485/25 mg | $615/50 mg | $240/1 mL (in DMSO) | $2,495/5x50 mg
Chemical Structure
AD80, Inhibitor (Cat# AAA5750442)
Full Name
AD80
Purity
100.0%
Pricing
$210/1 mg | $305/5 mg | $405/10 mg | $695/25 mg | $1,070/50 mg | $1,765/100 mg | $305/1 mL (in DMSO) | $7,680/5x100 mg
Chemical Structure
(Chemical structure of Src I1 (SIH-478), a Src kinase inhibitor. CAS #: 179248-59-0. Molecular Formula: C22H19N3O3. Molecular Weight: 373.4 g/mol.)
Src I1, Small Molecule (Cat# AAA808177)
Full Name
Src I1
Purity
>=98% (TLC)
Pricing
$190/5 mg | $365/25 mg | $1,415/5x25 mg | $620/5x5 mg
SNIP, Polyclonal Antibody (Cat# AAA9507193)
Full Name
SNIP Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Pricing
$265/0.05 mL | $365/0.1 mL | $1,580/5x0.1 mL
Structure
KX2-391, Inhibitor (Cat# AAA578896)
Full Name
KX2-391
Purity
99.4%
Pricing
$185/2 mg | $210/5 mg | $250/10 mg | $335/25 mg | $490/50 mg | $745/100 mg | $210/1 mL (in DMSO) | $3,080/5x100 mg
Src I 1, Inhibitor (Cat# AAA579708)
Full Name
Src I 1
Purity
99.8%
Pricing
$190/2 mg | $215/5 mg | $240/10 mg | $340/25 mg | $510/50 mg | $735/100 mg | $210/1 mL (in DMSO) | $3,040/5x100 mg
SDS-Page
(Recombinant LCK protein 10% SDS-PAGE with Coomassie staining MW: 59.3 kDa Purity: >90%)
LCK, Recombinant Protein (Cat# AAA389428)
Full Name
Recombinant LCK protein
Gene Names
LCK; LSK; YT16; p56lck; pp58lck
Pricing
$545/0.02 mg | $4,100/1 mg | $18,390/5x1 mg
CP-724714, Inhibitor (Cat# AAA579919)
Full Name
CP-724714
Purity
98.82%
Pricing
$205/2 mg | $235/5 mg | $295/10 mg | $430/25 mg | $595/50 mg | $835/100 mg | $235/1 mL (in DMSO) | $3,495/5x100 mg
Structure
Tirbanibulin dihydrochloride, Inhibitor (Cat# AAA5755054)
Full Name
Tirbanibulin dihydrochloride
Purity
98.00%
Pricing
$210/5 mg | $250/10 mg | $485/50 mg | $735/100 mg | $215/1mL*10mM (in DMSO) | $3,020/5x100 mg
p140Cap, Polyclonal Antibody (Cat# AAA9450017)
Full Name
p140Cap Polyclonal Conjugated Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
Most Applications
Pricing
$480/0.1 mL (Biotin) | $480/0.1 mL (AF350) | $480/0.1 mL (AF405) | $480/0.1 mL (AF488) | $480/0.1 mL (AF555) | $480/0.1 mL (AF594) | $480/0.1 mL (AF647) | $480/0.1 mL (AF680) | $480/0.1 mL (AF750)
UM-164, Inhibitor (Cat# AAA5750682)
Full Name
UM-164
Purity
98.00%
Pricing
$200/2 mg | $230/5 mg | $460/25 mg | $705/50 mg | $2,905/5x50 mg
Western Blot (WB)
(Western blot analysis of extracts from HepG2 and HeLa cells, using SNIP antibody. )
SRCIN1, Polyclonal Antibody (Cat# AAA7131777)
Full Name
SRCIN1 Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human
Applications
EIA, WB
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$260/0.1 mL | $1,155/5x0.1 mL
Western Blot (WB)
(Western Blot analysis of HeLa cells using p140Cap Polyclonal Antibody)
SRCIN1, Polyclonal Antibody (Cat# AAA7122247)
Full Name
SRCIN1 Antibody
Gene Names
SRCIN1; P140; SNIP
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pricing
$140/0.05 mg | $180/0.1 mg | $800/5x0.1 mg
