Western Blot (WB)
(Western blot analysis of p140 Cap expression in HEK293T (A), HeLa (B) whole cell lysates.)
Rabbit p140 Cap Polyclonal Antibody | anti-SRCIN1 antibody
Anti-p140 Cap Antibody
Western Blot (WB)
(Western blot analysis of p140 Cap expression in HEK293T (A), HeLa (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of p140 Cap expression in HEK293T (A), HeLa (B) whole cell lysates.)
NCBI and Uniprot Product Information
Uniprot Description
SNIP: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. Interacts with the N-terminal coiled-coil region of SNAP25. Interacts with BCAR1/p130Cas and SRC through its C-terminal domain. Interacts with CSK, CTTN, SORBS3/vinexin, SYP and MAPRE3/EB3. Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue. Belongs to the SRCIN1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: postsynaptic membrane; focal adhesion; axon; cytoplasm; postsynaptic density; dendrite; synapse; actin cytoskeleton
Molecular Function: protein binding; protein kinase binding
Biological Process: exocytosis; regulation of cell migration
Research Articles on SRCIN1
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Product Notes
The SRCIN1 srcin1 (Catalog #AAA8221699) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-p140 Cap Antibody reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's p140 Cap can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the SRCIN1 srcin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p140 Cap, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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