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7 results for " phospho TrkA Tyr490 " - showing 1-7
Western Blot (WB)
(Western blot analysis of extracts of NIH/3T3 cells treated with BDNF, using Phospho-TrkA (Tyr490) Antibody.)
TrkA, Polyclonal Antibody (Cat# AAA9600757)
Full Name
Phospho-TrkA (Tyr490) Antibody
Gene Names
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Pricing
$260/0.1 mL | $310/0.2 mL | $1,330/5x0.2 mL
Testing Data
(Images: Increased mobilization of trkA to neuronal membrane enhances response to NGF challenge. A, Fluorescence photomicrographs depicting relative levels of activated/phosphorylated trkA (phospho-trkA) detected under permeabilizing conditions in representative adult DRG neurons exposed to acidic (pH 6.5) or control (pH 7.4) media (in the presence of anti-BDNF) for 30 min, followed by a 15 min challenge with pH-specific medium + anti-BDNF alone or with anti-BDNF + 50 ng/ml NGF. Scale bar, 10 μm. Scatter plots illustrate the relationship between phospho-trkA-like labeling intensity (y-axis; normalized to the mean signal intensity from the control pH group) and perikaryal diameter (x-axis) for all sensory neurons analyzed from three separate experiments exposed to control (pH 7.4, B) or acidic (pH 6.5, C) media as above and then challenged with 50 ng/ml NGF (open circles) or not (filled circles). D, Summary bar graph depicting relative levels of activated trkA (phospho-trkA; normalized to pH 7.4 control) in representative adult DRG neurons exposed to acidic (pH 6.5) or control (pH 7.4) media for 30 min and then challenged with 50 ng/ml NGF and as normalized to the mean signal intensity from the control pH group. E, Fluorescence photomicrographs of sensory neurons exposed to identical conditions as in A and processed to detect activated/phosphorylated p38MAPK Note: A significant increase is observed in the levels of phospho-trkA detected in sensory neurons in response to acidosis with a parallel response observed for phospho-p38MAPK (E) (one-way ANOVA with post hoc Tukey's; ***p < 0.001; n = 131-210 neurons analyzed per experimental condition). Scale bar, 20 μm. The Journal of Neuroscience, 8 May 2013, 33(19): 8202-8215; doi: 10.1523/JNEUROSCI.4408-12.2013-phospho-TrkA Customer Publications.)
TrkA (Tyr490), Antibody (Cat# AAA555286)
Full Name
Phospho-TrkA (Tyr490), Affinity Purified Antibody, Rabbit
Reactivity
Human, Rat
Applications
IP, IHC, WB
Pricing
$620/0.1 mL | $2,650/5x0.1 mL
TrkA, Polyclonal Antibody (Cat# AAA641485)
Full Name
TrkA, Phosphorylated (Tyr490) (High Affinity Nerve Growth Factor Receptor, Neurotrophic Tyrosine Kinase Receptor Type 1, TRK1-transforming Tyrosine Kinase Protein, Tropomyosin-related Kinase A, Tyrosine Kinase Receptor, Tyrosine Kinase Receptor A, Trk-A,
Reactivity
Human, Mouse, Rat
Applications
WB, IP, ICC
Purity
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Pricing
$645/0.1 mg | $2,900/5x0.1 mg
TrkA, Blocking Peptide (Cat# AAA9615313)
Full Name
Phospho-TrkA (Tyr490) Blocking Peptide
Gene Names
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Applications
Blocking/Control
Purity
The purity is >90%,tested by HPLC and MS.
Pricing
$380/1 mg | $1,650/5x1 mg
TrkA/TrkB, Polyclonal Antibody (Cat# AAA8576032)
Full Name
Phospho-TrkA (tyr490)/TrkB (Tyr516) Rabbit pAb
Gene Names
NTRK2; TRKB; trk-B; GP145-TrkB
Reactivity
Human
Applications
WB
Purity
Affinity purified
Pricing
$310/0.1 mL | $570/0.1 mL (Biotin) | $1,330/5x0.1 mL | $570/0.1 mL (FITC) | $570/0.1 mL (AF350) | $570/0.1 mL (AF405) | $570/0.1 mL (AF488) | $570/0.1 mL (AF555) | $570/0.1 mL (AF568)
Western Blot (WB)
(Western blot detection of Phospho-TrkA (tyr490)/TrkB (Tyr516) in K562,C6,3T3 cell lysates using Phospho-TrkA (tyr490)/TrkB (Tyr516) Rabbit mAb(1:1000 diluted). Predicted band size:92kDa. Observed band size:140kDa.)
TrkA, Monoclonal Antibody (Cat# AAA4752524)
Full Name
Phospho-TrkA (tyr490)/TrkB (Tyr516) Rabbit mAb
Gene Names
NTRK2; TRKB; trk-B; GP145-TrkB
Reactivity
Human
Applications
WB
Purity
Affinity purified
Pricing
$440/0.1 mL | $1,530/5x0.1 mL
TrkA, Polyclonal Antibody (Cat# AAA9463024)
Full Name
phospho-TrkA (Tyr490) Polyclonal Antibody FITC Conjugated
Gene Names
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Reactivity
Human, Mouse, Rat
Applications
FC/FACS, ICC, IF
Purity
affinity purified by Protein A
Pricing
$595/0.1 mL | $2,525/5x0.1 mL
